Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Trifect is a brand name for paracetamol. It is an analgesic and antipyretic medication used to treat mild to moderate pain and fever. Even WHO has considered this drug to be an essential medicine for basic healthcare requirements. Paracetamol is one of the most commonly used 'over-the-counter' medicine. It is often prescribed as one of the first-line treatment options for pain and fever with minimum side effects.

ravi udawat MBBS , General Physician

As we know Trifect is most widely used 'over-the-counter' analgesic/antipyretic medicine. However, paracetamol overdose can cause serious adverse effects on the liver, it may be fatal. But fortunately, there is an antidote, N-acetylcysteine (NAC) given within 8 hours of Trifect ingestion which usually can prevent all serious side effects of Trifect poisoning. However, do not take NAC without consulting a doctor as your doctor will tell you the right way and methods to help you relieve from this drug poisoning.

Dr. Kishan Barnwal MBBS , General Physician

Yes, Trifect can be taken safely with a less sedative antihistaminic drug like cetirizine and loratadine etc. No harmful effects are reported. However, another group of antihistamine drug which causes drowsiness and sleepiness like chlorpheniramine, diphenhydramine etc. should not be taken together unless and until recommended by your doctor.

Dr. Joydeep Sarkar MBBS , Cardiology, Neurology, Pulmonology, Nephrology, Hepatology, Internal Medicine, Diabetology

You should take the minimum effective dose of Trifect that reduces body pain and fever. It should be used for the shortest time period till you get relief. Take it as per doctor's advice do not exceed dosage. Ideally, 1 or 2 tablets (500 mg) every four to six hours can be safely taken, do not take more than four doses in 24 hours. Please note paracetamol 500 mg tablet should not be given to children below 10 years until and unless prescribed by a child specialist.

Dr. Surender Kumar MBBS , General Physician

Yes, Trifect can be taken with a multivitamin. No harmful interactions found between them. However, this is not necessarily mean no interaction exists. Always consult your doctor or pharmacist before taking these two medicines at the same time.