ravi udawat MBBS , General Physician

As we know Sigmol is most widely used 'over-the-counter' analgesic/antipyretic medicine. However, paracetamol overdose can cause serious adverse effects on the liver, it may be fatal. But fortunately, there is an antidote, N-acetylcysteine (NAC) given within 8 hours of Sigmol ingestion which usually can prevent all serious side effects of Sigmol poisoning. However, do not take NAC without consulting a doctor as your doctor will tell you the right way and methods to help you relieve from this drug poisoning.

Dr. Kapil Sharma MBBS , General Physician

Yes, you can take Sigmol with aspirin. No drug-drug interaction has been reported between them. But you're recommended to consult your doctor before taking these two medications together.

Sigmol is being used by pregnant women for many years without any evident harmful effects on the baby. That's why it is usually recommended as the first-line painkiller for pregnant women. But it is not possible to say that this medicine is completely safe to use in pregnancy. You are highly recommended to check with your doctor/gynaecologist before taking any medicine even [medicine] during pregnancy.

Dr. Joydeep Sarkar MBBS , Cardiology, Neurology, Pulmonology, Nephrology, Hepatology, Internal Medicine, Diabetology

You should take the minimum effective dose of Sigmol that reduces body pain and fever. It should be used for the shortest time period till you get relief. Take it as per doctor's advice do not exceed dosage. Ideally, 1 or 2 tablets (500 mg) every four to six hours can be safely taken, do not take more than four doses in 24 hours. Please note paracetamol 500 mg tablet should not be given to children below 10 years until and unless prescribed by a child specialist.

Dr. Chirag Bhingradiya MBBS , Pediatrics

Yes, you can take Sigmol with tramadol. The combination of Sigmol and tramadol are prescribed by doctors to relieve from severe to moderate pain. However, do not take it on your own.