Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Perfalgan is a brand name for paracetamol. It is an analgesic and antipyretic medication used to treat mild to moderate pain and fever. Even WHO has considered this drug to be an essential medicine for basic healthcare requirements. Paracetamol is one of the most commonly used 'over-the-counter' medicine. It is often prescribed as one of the first-line treatment options for pain and fever with minimum side effects.

Dr. Joydeep Sarkar MBBS , Cardiology, Neurology, Pulmonology, Nephrology, Hepatology, Internal Medicine, Diabetology

You should take the minimum effective dose of Perfalgan that reduces body pain and fever. It should be used for the shortest time period till you get relief. Take it as per doctor's advice do not exceed dosage. Ideally, 1 or 2 tablets (500 mg) every four to six hours can be safely taken, do not take more than four doses in 24 hours. Please note paracetamol 500 mg tablet should not be given to children below 10 years until and unless prescribed by a child specialist.

Dr. K. M. Bhatt MBBS, PG Dip , Cardiology, Pediatrics, General Surgery, General Physician, Emergency Medicine, Physical Medicine

Yes, you can take Perfalgan with or without food, because it doesn't irritate the stomach lining, unlike other drugs. However, if you are taking NSAIDs (painkillers) such as Aspirin and Ibuprofen along with paracetamol it is best to take them with a light meal or a glass of milk.

ravi udawat MBBS , General Physician

An overdose occurs when more than the required amount (toxic levels) of [medicine] is taken. Initial symptoms of Perfalgan overdose includes loss of appetite, drowsiness, seizures, abdominal pain, nausea, and vomiting. Later progressive symptoms may include pain in your upper stomach, dark colored urine, yellowing of your skin or the white patches in your eyes, liver damage and in rare cases, it can also lead to coma. So, by any chance, if you have accidentally taken more than the required dose of Perfalgan inform your doctor immediately.

Although it's believed that Perfalgan works mainly in the central nervous system (Brain and Spine). It prevents the release of prostaglandin, which is responsible for increasing pain and body temperature. It effectively reduces the intensity of pain signals to the brain.