Although it's believed that Parabig works mainly in the central nervous system (Brain and Spine). It prevents the release of prostaglandin, which is responsible for increasing pain and body temperature. It effectively reduces the intensity of pain signals to the brain.

Dr. Haleema Yezdani MBBS , General Physician

Parabig is primarily used to reduce pain and fever. It can a for other conditions such as a headache, muscle aches, backache, toothaches, and colds.

ravi udawat MBBS , General Physician

As we know Parabig is most widely used 'over-the-counter' analgesic/antipyretic medicine. However, paracetamol overdose can cause serious adverse effects on the liver, it may be fatal. But fortunately, there is an antidote, N-acetylcysteine (NAC) given within 8 hours of Parabig ingestion which usually can prevent all serious side effects of Parabig poisoning. However, do not take NAC without consulting a doctor as your doctor will tell you the right way and methods to help you relieve from this drug poisoning.

Dr. Kuldeep Meena MBBS, MD , Cardiology, Neurology, Pediatrics, Dermatology, Pulmonology, Nephrology, General Physician, Other, Infectious Disease, Emergency Medicine, Allergy and Immunology, Internal Medicine, Multispeciality

No harmful interactions have been reported between Parabig and codeine. Do not take it until and unless prescribed. However, if you are experiencing any unpleasant medicinal side effects such as nausea, stomach pain, and tremors after taking Parabig. Inform your doctor immediately.

Dr. Joydeep Sarkar MBBS , Cardiology, Neurology, Pulmonology, Nephrology, Hepatology, Internal Medicine, Diabetology

You should take the minimum effective dose of Parabig that reduces body pain and fever. It should be used for the shortest time period till you get relief. Take it as per doctor's advice do not exceed dosage. Ideally, 1 or 2 tablets (500 mg) every four to six hours can be safely taken, do not take more than four doses in 24 hours. Please note paracetamol 500 mg tablet should not be given to children below 10 years until and unless prescribed by a child specialist.