ravi udawat MBBS , General Physician

As we know Metacin is most widely used 'over-the-counter' analgesic/antipyretic medicine. However, paracetamol overdose can cause serious adverse effects on the liver, it may be fatal. But fortunately, there is an antidote, N-acetylcysteine (NAC) given within 8 hours of Metacin ingestion which usually can prevent all serious side effects of Metacin poisoning. However, do not take NAC without consulting a doctor as your doctor will tell you the right way and methods to help you relieve from this drug poisoning.

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Metacin is a brand name for paracetamol. It is an analgesic and antipyretic medication used to treat mild to moderate pain and fever. Even WHO has considered this drug to be an essential medicine for basic healthcare requirements. Paracetamol is one of the most commonly used 'over-the-counter' medicine. It is often prescribed as one of the first-line treatment options for pain and fever with minimum side effects.

Although it's believed that Metacin works mainly in the central nervous system (Brain and Spine). It prevents the release of prostaglandin, which is responsible for increasing pain and body temperature. It effectively reduces the intensity of pain signals to the brain.

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Metacin is a safe drug no much precautions are to be taken. However, alcohol should be completely avoided. If you have any previous history of kidney and liver diseases keep your doctor informed before taking this drug.

Dr. K. M. Bhatt MBBS, PG Dip , Cardiology, Pediatrics, General Surgery, General Physician, Emergency Medicine, Physical Medicine

Yes, you can take Metacin with or without food, because it doesn't irritate the stomach lining, unlike other drugs. However, if you are taking NSAIDs (painkillers) such as Aspirin and Ibuprofen along with paracetamol it is best to take them with a light meal or a glass of milk.