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Otisafe is a prescription medicine that is available as a Drops. Bacterial Infections, Fungal Infections, Candidal Infection are some of its major therapeutic uses. The alternative uses of Otisafe have also been explained below.
Medical history of the patient along with age and gender determines the dosage of Otisafe. The condition it has been prescribed for, and the route of administration also determine the right dosage. For detailed information on this, read through the dosage section.
Apart from the aforementioned side effects, Otisafe can also lead to other problems, which have been listed below. Normally, these side effects of Otisafe are not long lasting and go away when the treatment is finished. However, if these continue for a longer time, consult your doctor right away.
Furthermore, you should know that effect of Otisafe is Unknown for pregnant women and Moderate for women who are breastfeeding. Further, the section on Otisafe related warnings talks about Otisafe's effects on the liver, heart and kidney.
Otisafe can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Otisafe in conditions like Kidney Disease, Liver Disease. Other conditions have been mentioned below in the Otisafe contraindications section.
Drug reaction of Otisafe with other medicines has been reported. Refer to the list below for further details.
In addition to these precautions, you may also note that Otisafe is safe while driving, and is is addictive in nature.
Otisafe is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Is the use of Otisafe safe for pregnant women?
Side effects of Otisafe during pregnancy are not known because scientific research on this topic hasn't been done.
Is the use of Otisafe safe during breastfeeding?
Otisafe may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Otisafe, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Otisafe.
What is the effect of Otisafe on the Kidneys?
Otisafe rarely affects the kidneys.
What is the effect of Otisafe on the Liver?
Otisafe may have mild side effects on the liver. Most people will never see any effect on the liver.
What is the effect of Otisafe on the Heart?
Otisafe is rarely harmful for the heart.
Otisafe should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Otisafe unless your doctor advises you to do so -
Is this Otisafe habit forming or addictive?
Otisafe does not cause addiction.
Interaction between Food and Otisafe
Information is not available on the interaction of any foods with Otisafe, due to a lack of research on this.
Interaction between Alcohol and Otisafe
Due to lack of research, there is no information about the side effects of taking Otisafe with alcohol.
No, Otisafe does not cover Pseudomonas species. They are generally found to be resistant to Otisafe.
Otisafe is bacteriostatic at the therapeutic dose that means it inhibits the growth of the bacteria but it can be bactericidal at higher doses. It works by inhibiting the protein synthesis in bacteria which it needs to survive. In the absence of protein synthesis, the bacterial growth is stunned and slowed.
Yes, Otisafe can treat meningitis. It is a bacterial infection caused by Neisseria meningitidis that causes inflammation of the meninges around the brain and spinal cord. The duration of the treatment is usually 2 weeks.
Yes, Otisafe may cause gray baby syndorme in newborn infants especially in premature baby, if this drug is given in higher doses. Gray baby syndrome is a rare side effect that occurs due to accumulation of the chloramphenicol in the newborn infant. The cause of gray baby syndrome is that the newborn baby lacks the some liver enzymes which are necessary to metabolize and removes this drug from the body. The accumulation of the chloramphenicol in the body leads to toxicity which causes development of symptoms such as vomiting, gray color of the skin, blue discolouration of lips and skin. To avoid gray baby syndrome the doses of Otisafe must be lowered and adjusted as per the need.
Yes, Otisafe can be taken with ibuprofen. No harmful drug interaction has been reported between them. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Chloromycetin sodium succinate (chaloramphenicol sodium succinate)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 739-742
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 174-177
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 763,792
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Qvar® Redihaler™ (beclomethasone dipropionate HFA)
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 355-356
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 231
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; QVAR® (beclomethasone dipropionate HFA)