Dr. Vedprakash Verma MBBS, MD , Cardiology

Yes, Gluconorm is safe to use, many people have side effects at first, they usually diminish and then go away completely in a few weeks. A few people find they cannot tolerate metformin, there are other drugs but metformin is usually the first choice. It is very safe

Dr. Mayank Yadav MBBS , General Physician

Yes, Gluconorm commonly cause stomach upset like diarrhea, abdominal pain, nausea, and vomiting. To avoid these side effects you should take Gluconorm with your meal and increase the dose gradually.

Dr. Ramraj MBBS , Other

Yes, Gluconorm can cause low blood sugar (hypoglycemia). However, this can also occur if you delay or miss a meal, drink alcohol, exercise more than usual, can't eat due to stomach upset, and taking other antidiabetic medicine with metformin. So, regular monitoring of blood glucose level is needed and be cautious of symptoms of hypoglycemia, always keep glucose-rich food with you. 

Dr. Joydeep Sarkar MBBS , Internal Medicine

Yes, Gluconorm can cause night sweat, the exact mechanism of sweating is not known. But some research suggests that Gluconorm causes hypoglycemia (low blood sugar) especially at night which can cause night sweats. Need to monitor your blood glucose level regularly, and talk to your doctor as your dose of Gluconorm may need to be adjusted.

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Gluconorm treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Gluconorm induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst.