Dr. Ramraj Meena MBBS , General Physician

Yes, Clobiotic covers all anaerobes. It effectively inhibits most of the anaerobic bacteria at therapeutic doses. An antibiotic sensitivity test is always recommended to confirm its susceptibility.

Dr. Sameer Awadhiya MBBS , Pediatrics

Clobiotic contains chloramphenicol which is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It works by inhibiting the protein synthesis in bacteria which needs to survive. In the absence of protein, the bacterial growth is stunned and slowed. It can also kill the bacteria in higher doses. Clobiotic is effective against a wide range of both gram negative and gram positive bacteria such as Salmonella species, Rickettsia species, Neisseria meningitidis, Escherichia coli, Haemophilus influenzae, and Staphylococcus pneumoniae.

Dr. Tarun kumar MBBS , Other

Yes, Clobiotic may cause gray baby syndorme in newborn infants especially in premature baby, if this drug is given in higher doses. Gray baby syndrome is a rare side effect that occurs due to accumulation of the chloramphenicol in the newborn infant. The cause of gray baby syndrome is that the newborn baby lacks the some liver enzymes which are necessary to metabolize and removes this drug from the body. The accumulation of the chloramphenicol in the body leads to toxicity which causes development of symptoms such as vomiting, gray color of the skin, blue discolouration of lips and skin. To avoid gray baby syndrome the doses of Clobiotic must be lowered and adjusted as per the need.

Dr. MBBS , General Physician, Other, Obstetrics & Gynaecology

Yes, Clobiotic might cause aplastic anemia which is a type of anemia in which the body is not able to make new red blood cells. Clobiotic induces aplastic anemia by suppressing the red bone marrow which produces new red blood cells. However, it is reversible and the red blood cells production by red bone marrow is restored after discontinuation of this drug.

Dr. Ram Saini MD, MBBS , General Physician

Yes, Clobiotic has been reported to cause diarrhoea and it is the most common side effect of this medicine. Drink plenty of fluids while you are taking this medicine. If you are experiencing severe diarrhoea after taking this drug, consult your doctor immediately without any further delay.