Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Yes, Polynase D can treat meningitis. It is a bacterial infection caused by Neisseria meningitidis that causes inflammation of the meninges around the brain and spinal cord. The duration of the treatment is usually 2 weeks.

Dr. Ramraj MBBS , Other

No, Polynase D does not cover Enterococcus faecalis. They are generally found to be resistant to Polynase D. However antibiotic sensitivity test is recommended to confirm its resistance. 

Dr. Piyush Malav MBBS, MS , General Surgery

Yes, Polynase D is helpful in typhoid fever. It is used in the management of acute typhoid fever caused by Salmonella species. It is usually given after 8 -10 days of the treatment when the fever of the patient is completely going down over this duration to prevent the relapse of the typhoid infection.

Dr. Sangita Shah MBBS , General Physician

Polynase D is bacteriostatic at the therapeutic dose that means it inhibits the growth of the bacteria but it can be bactericidal at higher doses. It works by inhibiting the protein synthesis in bacteria which it needs to survive. In the absence of protein synthesis, the bacterial growth is stunned and slowed.

Dr. Tarun kumar MBBS , Other

Yes, Polynase D may cause gray baby syndorme in newborn infants especially in premature baby, if this drug is given in higher doses. Gray baby syndrome is a rare side effect that occurs due to accumulation of the chloramphenicol in the newborn infant. The cause of gray baby syndrome is that the newborn baby lacks the some liver enzymes which are necessary to metabolize and removes this drug from the body. The accumulation of the chloramphenicol in the body leads to toxicity which causes development of symptoms such as vomiting, gray color of the skin, blue discolouration of lips and skin. To avoid gray baby syndrome the doses of Polynase D must be lowered and adjusted as per the need.