Chloramphenicol + Dexamethasone

Yes, Chloramphenicol + Dexamethasone might cause aplastic anemia which is a type of anemia in which the body is not able to make new red blood cells. Chloramphenicol + Dexamethasone induces aplastic anemia by suppressing the red bone marrow which produces new red blood cells. However, it is reversible and the red blood cells production by red bone marrow is restored after discontinuation of this drug.

Yes, Chloramphenicol + Dexamethasone may cause gray baby syndorme in newborn infants especially in premature baby, if this drug is given in higher doses. Gray baby syndrome is a rare side effect that occurs due to accumulation of the chloramphenicol in the newborn infant. The cause of gray baby syndrome is that the newborn baby lacks the some liver enzymes which are necessary to metabolize and removes this drug from the body. The accumulation of the chloramphenicol in the body leads to toxicity which causes development of symptoms such as vomiting, gray color of the skin, blue discoloration of lips and skin. To avoid gray baby syndrome the doses of Chloramphenicol + Dexamethasone must be lowered and adjusted as per the need.

Chloramphenicol + Dexamethasone is a brand name of chloramphenicol and it comes in the various dosage forms such as an oral tablet, capsule, syrup, and eye drops. It is a prescription drug that belongs to the class of medications called amphenicols. It is a broad spectrum antibiotic which is active against a wide variety of gram-positive and gram-negative bacteria. It is mainly used in the treatment of psittacosis also known as parrot fever, rickettsial infection, cystic fibrosis, pneumonia, and also sometimes in the management of typhoid fever.

Yes, Chloramphenicol + Dexamethasone can be taken with paracetamol. No drug-drug interaction has been reported between them. Chloramphenicol + Dexamethasone is safe to take along with paracetamol if taken as recommended. 

Yes, Chloramphenicol + Dexamethasone may cause gray baby syndorme in newborn infants especially in premature baby, if this drug is given in higher doses. Gray baby syndrome is a rare side effect that occurs due to accumulation of the chloramphenicol in the newborn infant. The cause of gray baby syndrome is that the newborn baby lacks the some liver enzymes which are necessary to metabolize and removes this drug from the body. The accumulation of the chloramphenicol in the body leads to toxicity which causes development of symptoms such as vomiting, gray color of the skin, blue discolouration of lips and skin. To avoid gray baby syndrome the doses of Chloramphenicol + Dexamethasone must be lowered and adjusted as per the need.