Bortlee 2mg Injection

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Bortlee 2mg Injection

1 Injection in 1 Vial
₹ 5891
1 Injection | 1 Vial
₹ 5891
people have bought this recently
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Bortlee Information

Bortlee is an antineoplastic (anti-cancer) medication that belongs to the class of proteasome inhibitors. It is primarily used for the treatment of multiple myeloma and mantle cell lymphoma. By disrupting cellular processes, it helps to prevent cancer cells from growing and multiplying.

Uses

Multiple MyelomaBortlee is often used as a first-line treatment in combination with other drugs such as dexamethasone or lenalidomide.

Mantle Cell Lymphoma (MCL): It is approved for the treatment of MCL in patients who have received at least one prior therapy.

Bortlee inhibits the 26S proteasome, a protein complex involved in breaking down unneeded or damaged proteins. By inhibiting the proteasome, Bortlee induces apoptosis (programmed cell death) in cancer cells, disrupting their survival mechanisms.



Bortlee Benefits & Uses

Bortlee is used to treat the following -

Main Benefits

Other Benefits

Bortlee Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Multiple Myeloma
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: 2 weeks
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Multiple Myeloma
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: 2 weeks
  • Special Instructions: As prescribed by the doctor

Bortlee Related Warnings

  • Is the use of Bortlee safe for pregnant women?


    Bortlee shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Bortlee safe during breastfeeding?


    Bortlee may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

    Severe
  • What is the effect of Bortlee on the Kidneys?


    There are no side effects of Bortlee on the kidneys.

    Safe
  • What is the effect of Bortlee on the Liver?


    The liver can be affected by Bortlee. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Bortlee only after medical advice.

    Moderate
  • What is the effect of Bortlee on the Heart?


    Bortlee can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate


Severe Interaction of Bortlee with Other Drugs

Bortlee should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Bortlee Contraindications

If you are suffering from any of the following diseases, you should not take Bortlee unless your doctor advises you to do so -



Frequently asked Questions about Bortlee

  • Is this Bortlee habit forming or addictive?


    No, you will not get addicted to Bortlee.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Bortlee as you may feel sleepy.

    Dangerous
  • Is it safe?


    Yes, but consume Bortlee only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Bortlee in mental disorders is not effective.

    No

Bortlee Interactions with Food and Alcohol

  • Interaction between Food and Bortlee


    Taking Bortlee with some specific foods may delay its effect. Talk to your doctor about this.

    Mild
  • Interaction between Alcohol and Bortlee


    Due to lack of research, there is no information about the side effects of taking Bortlee with alcohol.

    Unknown


See all substitutes for Bortlee


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 234-235

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 871

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Velcade® (bortezomib)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Bortezomib Aft (Bortezomib)



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