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OTC Medicines for Mantle Cell Lymphoma
What is Mantle Cell Lymphoma?
Mantle Cell Lymphoma (MCL) is a type of non-Hodgkin lymphoma, which is aggressive and rare. In MCL, the lymphoma originates from the mantle zone or the corona of the lymph node. Mantle cell lymphoma generally involves the digestive tract and the bone marrow.
What are its main signs and symptoms?
MCL has symptoms similar to that of other lymphomas. The early symptoms of MCL can be easily overlooked or taken as common health issues. Some of the early symptoms of MCL are:
- Swollen lymph nodes of the neck or groin or the armpits
- Fatigue
- Unsteady or intermittent fever
- Night Sweats
- Sudden and unexplained weight loss
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Some of the advanced stage symptoms of MCL are:
- Bone pain
- Trouble in breathing
- Prolonged weakness and tiredness
- Increase in the above-mentioned symptoms
What are its main causes?
MCL has several causes and yet the exact reason which leads to MCL is unknown. More than 90% of the patients with MCL are found to have an overproduction of the protein cyclin D1. Also found in excess are proteins like lactate dehydrogenase and beta 2 microglobulin.
How is it diagnosed and treated?
If the patient’s symptoms indicate a possible lymph tumour or cancer, then the doctor or pathologist will suggest a biopsy to examine and determine the kind of cell present in the cancerous growth.
On detection of lymphoma cells, further tests are carried out which include X-rays of the chest, blood tests, along with, imaging scans like computed tomography (CT) or magnetic resonance imaging (MRI) to determine the growth and identify the affected areas.
The treatment of MCL is carried out based upon the stage of cancer.
The most common treatment in the early stages are medicinal/ pharmacologic; however, in the later stages, chemotherapy and radiation therapy are introduced. Drugs such as rituximab, which target the cancerous B-cells are also found to be useful in advanced stages. In special cases of severe immune weakness, doctors carry out a bone marrow or stem cell transplant, which helps in building new and healthy immune cells.
