Myzomib

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Myzomib Information

Myzomib is an antineoplastic (anti-cancer) medication that belongs to the class of proteasome inhibitors. It is primarily used for the treatment of multiple myeloma and mantle cell lymphoma. By disrupting cellular processes, it helps to prevent cancer cells from growing and multiplying.

Uses

Multiple MyelomaMyzomib is often used as a first-line treatment in combination with other drugs such as dexamethasone or lenalidomide.

Mantle Cell Lymphoma (MCL): It is approved for the treatment of MCL in patients who have received at least one prior therapy.

Myzomib inhibits the 26S proteasome, a protein complex involved in breaking down unneeded or damaged proteins. By inhibiting the proteasome, Myzomib induces apoptosis (programmed cell death) in cancer cells, disrupting their survival mechanisms.


Myzomib Benefits & Uses

Myzomib is used to treat the following -

Main Benefits

Other Benefits

Myzomib Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Multiple Myeloma
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: 2 weeks
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Multiple Myeloma
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: 2 weeks
  • Special Instructions: As prescribed by the doctor

Myzomib Side Effects

Based on research, the following side effects have been observed when Myzomib is used -

Severe

Moderate

  • Bone Pain
  • Orthostatic Hypotension (Sudden Lowering of Blood Pressure on Standing)

Mild

Myzomib Related Warnings

  • Is the use of Myzomib safe for pregnant women?


    Myzomib has many dangerous side effects in pregnant women. If you are pregnant, do not consume Myzomib without medical advice.

    Severe
  • Is the use of Myzomib safe during breastfeeding?


    Myzomib should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Myzomib on the Kidneys?


    There are no side effects of Myzomib on the kidneys.

    Safe
  • What is the effect of Myzomib on the Liver?


    Myzomib can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Myzomib on the Heart?


    There may be an adverse effect on the heart after taking Myzomib. If you observe any side effects on your body then stop taking this drug. Restart this medicine only if your doctor advises you to do so.

    Moderate

Severe Interaction of Myzomib with Other Drugs

Myzomib should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Myzomib Contraindications

If you are suffering from any of the following diseases, you should not take Myzomib unless your doctor advises you to do so -


Frequently asked Questions about Myzomib

  • Is this Myzomib habit forming or addictive?


    Forming a habit of Myzomib has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Myzomib, you should not drive or work on any heavy machine, as Myzomib can make you drowsy.

    Dangerous
  • Is it safe?


    Yes, but consume Myzomib only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Myzomib in mental disorders is not effective.

    No

Myzomib Interactions with Food and Alcohol

  • Interaction between Food and Myzomib


    Taking Myzomib with some specific foods may delay its effect. Talk to your doctor about this.

    Mild
  • Interaction between Alcohol and Myzomib


    Due to lack of research, there is no information about the side effects of taking Myzomib with alcohol.

    Unknown

See all substitutes for Myzomib


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 234-235

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 871

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Velcade® (bortezomib)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Bortezomib Aft (Bortezomib)


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