Duloxetine Capsule - Duzela 20 Capsule

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    Duloxetine Information

    Duloxetine is a prescription medicine. It is typically used for the treatment of Depression, Anxiety, Diabetic Neuropathy. Secondary and off-label uses of Duloxetine have also been mentioned below.

    Medical history of the patient along with age and gender determines the dosage of Duloxetine. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.

    Apart from the aforementioned side effects, Duloxetine can also lead to other problems, which have been listed below. Such side effects of Duloxetine normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

    Duloxetine's effect during pregnancy is Moderate and Severe while nursing. It is important to know if Duloxetine has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Duloxetine related warnings section.

    Individuals suffering from medical conditions like Kidney Disease, Liver Disease must refrain from the use of Duloxetine since this can cause severe adverse effects. Some other conditions that can be affected by Duloxetine are listed in the contraindications section below.

    Besides this, Duloxetine may also have severe interaction with some medicines. A complete list of these interactions is given below.

    Along with the above-mentioned precautions, remember that taking Duloxetine is considered not safe while driving, and is not addictive.



    Duloxetine Benefits & Uses

    Duloxetine is used to treat the following -

    Other Benefits

    Duloxetine Dosage & How to Take

    This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

    Find the right dosage based on disease and age

    Age Group Dosage
    Adult
    • Disease: Depression
    • Before or After Meal: After Meal
    • Single Maximum Dose: 30 mg
    • Dosage Form: Tablet
    • Dosage Route: Oral
    • Frequency: 2 daily
    • Course Duration: As directed by the doctor
    • Special Instructions: For course duration follow doctor's advice
    Geriatric
    • Disease: Depression
    • Before or After Meal: After Meal
    • Single Maximum Dose: 30 mg
    • Dosage Form: Tablet
    • Dosage Route: Oral
    • Frequency: 2 daily
    • Course Duration: As directed by the doctor
    • Special Instructions: For course duration follow doctor's advice
    13 - 18 years (Adolescent)
    • Disease: Anxiety
    • Before or After Meal: After Meal
    • Single Maximum Dose: 60 mg
    • Dosage Form: Tablet
    • Dosage Route: Oral
    • Frequency: 1 daily
    • Course Duration: As directed by the doctor
    • Special Instructions: For course duration follow doctor's advice


    Duloxetine Side Effects

    Based on research, the following side effects have been observed when Duloxetine is used -

    Moderate

    Mild

    Duloxetine Related Warnings

    • Is the use of Duloxetine safe for pregnant women?


      Duloxetine can cause unwanted side effects in pregnant women. If you experience any side effects, stop taking Duloxetine right away. Take your doctor's advice before taking it again.

      Moderate
    • Is the use of Duloxetine safe during breastfeeding?


      Women who are breastfeeding may experience severe harmful effects after taking Duloxetine. It should only be taken after medical advice.

      Severe
    • What is the effect of Duloxetine on the Kidneys?


      Duloxetine rarely affects the kidneys.

      Mild
    • What is the effect of Duloxetine on the Liver?


      Duloxetine has very mild side effects on the liver.

      Mild
    • What is the effect of Duloxetine on the Heart?


      Duloxetine has very mild side effects on the heart.

      Mild


    Severe Interaction of Duloxetine with Other Drugs

    Duloxetine should not be taken with following medicines due to severe side effects it may cause to patients -

    Severe

    Moderate



    Duloxetine Contraindications

    If you are suffering from any of the following diseases, you should not take Duloxetine unless your doctor advises you to do so -



    Frequently asked Questions about Duloxetine

    • Is this Duloxetine habit forming or addictive?


      No, you will not get addicted to Duloxetine.

      No
    • Is it safe to drive or operate heavy machinery when consuming?


      No, you should not drive or operate heavy machinery after taking Duloxetine as you may feel sleepy.

      Dangerous
    • Is it safe?


      Duloxetine should be used only after doctor's advice.

      Safe, but take only on Doctor's advise
    • Is it able to treat mental disorders?


      Duloxetine has been seen to have positive effect on patients with mental disorders.

      Yes

    Duloxetine Interactions with Food and Alcohol

    • Interaction between Food and Duloxetine


      Duloxetine may take longer to act if you eat some foods while taking it. Follow your doctor's advice on this.

      Mild
    • Interaction between Alcohol and Duloxetine


      Consult your doctor before consuming alcohol while taking Duloxetine as it can have severe side effects.

      Severe


    See all substitutes for Duloxetine


    This medicine data has been created by -

    Vikas Chauhan

    B.Pharma, Pharmacy
    5 Years of Experience


    References

    April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 474-475

    KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 462

    US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Cymbalta (duloxetine hydrochloride)

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