Depxit

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Depxit Information

Depxit is a prescription drug, available for use as Capsule. Fungal Infections, Candidal Infection, Urinary Tract Infection are some of its major therapeutic uses. Secondary and off-label uses of Depxit have also been mentioned below.

The correct dosage of Depxit depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. For detailed information on this, read through the dosage section.

While these are the most often observed Depxit side effects, there are can be others also. These have been listed below. These side effects of Depxit are usually temporary and subside with the completion of treatment. However, if these continue for a longer time, consult your doctor right away.

In addition, Depxit's effect is Severe during pregnancy and Safe for lactating mothers. In addition, Depxit's effects on the liver, heart and kidney are discussed below in the Depxit related warnings section.

Depxit is contraindicated in people with pre-existing medical conditions like Liver Disease as it can result in adverse effects. The section on Depxit contraindications lists all such conditions.

Drug interactions for Depxit have been reported in the medical literature. See below for a complete list.

In addition to the above precautions for Depxit, it is important to know that it is not safe while driving, and is not habit-forming.


Depxit Benefits & Uses

Depxit is used to treat the following -

Other Benefits

Depxit Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult(Female)
  • Disease: Vaginal Yeast Infection
  • Before or After Meal: After Meal
  • Single Maximum Dose: 150 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 3 days
  • Special Instructions: Then once a week for 6 months
Adult
  • Disease: Fungal Infections
  • Before or After Meal: After Meal
  • Single Maximum Dose: 400 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 1 days
  • Special Instructions: Then 200 - 800 mg/day for 28 days
Geriatric
  • Disease: Fungal Infections
  • Before or After Meal: After Meal
  • Single Maximum Dose: 400 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 1 days
  • Special Instructions: Then 200 - 800 mg/day for 28 days
13 - 18 years (Adolescent)
  • Disease: Fungal Infections
  • Before or After Meal: After Meal
  • Single Maximum Dose: 12 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 4 weeks
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Fungal Infections
  • Before or After Meal: After Meal
  • Single Maximum Dose: 6 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 4 weeks
  • Special Instructions: As prescribed by the doctor

Depxit Related Warnings

  • Is the use of Depxit safe for pregnant women?


    Depxit shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Depxit safe during breastfeeding?


    Depxit is completely safe for breastfeeding women.

    Safe
  • What is the effect of Depxit on the Kidneys?


    Depxit may cause harmful effects on kidney. if you feel its having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Depxit on the Liver?


    Very few cases of side effects of Depxit on the liver have been reported.

    Mild
  • What is the effect of Depxit on the Heart?


    Very few cases of side effects of Depxit on the heart have been reported.

    Mild

Severe Interaction of Depxit with Other Drugs

Depxit should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild


Depxit Contraindications

If you are suffering from any of the following diseases, you should not take Depxit unless your doctor advises you to do so -


Frequently asked Questions about Depxit

  • Is this Depxit habit forming or addictive?


    No, you will not get addicted to Depxit.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Depxit as you may feel sleepy.

    Dangerous
  • Is it safe?


    Depxit is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Depxit in mental disorders is not effective.

    No

Depxit Interactions with Food and Alcohol

  • Interaction between Food and Depxit


    Taking Depxit with food is safe.

    Safe
  • Interaction between Alcohol and Depxit


    No research has been done on this till date. Therefore, it is not known what the effect of taking Depxit with alcohol will be.

    Unknown

Frequently asked Questions about Depxit

Question over 5 years ago

Is Depxit nephrotoxic?

Dr. R.K Singh MBBS , Diabetology

No, Usually Depxit does not cause nephrotoxicity. But as per FDA reports patients above 65 years have exhibited acute renal failure hence elderly patients should take Depxit only when prescribed. However, the exact mechanism of renal failure associated with this drug is not yet known.

Question about 5 years ago

Does Depxit treat eczema?

Dr. Surender Kumar MBBS , General Physician

No, ideally Depxit is not used for treating eczema because it is not an antifungal infection. Please consult a doctor for the better medication options.

Question over 5 years ago

Is Depxit safe to use?

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

Yes, Depxit is safe to use, if taken in a prescribed amount for a specified time as advised by the doctor, however, few side effects are observed such as indigestion, stomach pain, diarrhea, and nausea.

Question over 5 years ago

Does Depxit treat jock itch?

Dr. MBBS , General Physician, Other, Infectious Disease

Yes, Depxit is widely used in the treatment of jock itch (tinea cruris). It is a prescription medicine so please consult your doctor before using this medication for tinea cruris.

Question almost 6 years ago

How does Depxit work?

Dr. Manoj Meena MBBS , General Physician

Depxit inhibit the fungal cytochrome P450 enzyme lanosterol 14- demethylase and thus block ergosterol synthesis leading to membrane abnormalities in the fungus. It kills the fungus by destroying its cell membrane.


See all substitutes for Depxit


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Diflucan® (fluconazole)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 793-794

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