Defnalone: Uses, Price, Dosage, Side Effects, Substitute, Buy Online

Defnalone Information

Defnalone, a prescription drug, is manufactured in various forms such as Tablet, Suspension. Allergy, Asthma, Rheumatic Disorder are some of its major therapeutic uses. Defnalone also has some secondary and off-label uses. These are listed below.

The correct dosage of Defnalone depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

Some other side effects of Defnalone have been listed ahead. Usually, these side effects of Defnalone go away soon, and do not persist beyond the duration of the treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

In addition, Defnalone's effect is Severe during pregnancy and Severe for lactating mothers. In addition, Defnalone's effects on the liver, heart and kidney are discussed below in the Defnalone related warnings section.

Defnalone can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Defnalone in conditions like Diabetes. Other conditions have been mentioned below in the Defnalone contraindications section.

Besides this, Defnalone may also have severe interaction with some medicines. A complete list of these interactions is given below.

You should also be aware that Defnalone is safe while driving, and is addiction.

Defnalone Benefits & Uses
Defnalone Dosage & How to Take
Defnalone Side Effects
Defnalone Related Warnings
Severe Interaction of Defnalone with Other Drugs
Defnalone Contraindications
Frequently asked Questions about Defnalone
Defnalone Interactions with Food and Alcohol

Defnalone Benefits & Uses

Defnalone is used to treat the following -

Main Benefits

Other Benefits

Defnalone Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Duchenne Muscular Dystrophy Before or After Meal: With meal Single Maximum Dose: 0.9 mg/kg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)	Disease: Duchenne Muscular Dystrophy Before or After Meal: With meal Single Maximum Dose: 0.9 mg/kg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor

Defnalone Side Effects

Based on research, the following side effects have been observed when Defnalone is used -

Severe

Bone degradation
Bone Fracture

Moderate

Electrolyte imbalance
Cataract
Depressed mood
Erythema

Mild

Headache
Acne
Nausea or vomiting

Defnalone Related Warnings

Is the use of Defnalone safe for pregnant women?

Defnalone shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

Severe
Is the use of Defnalone safe during breastfeeding?

Taking Defnalone may lead to serious side effects if you are breastfeeding. Defnalone should not be taken by breastfeeding women unless prescribed by the doctor.

Severe
What is the effect of Defnalone on the Kidneys?

Defnalone can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.

Moderate
What is the effect of Defnalone on the Liver?

Defnalone can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

Moderate
What is the effect of Defnalone on the Heart?

Defnalone may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

Moderate

Severe Interaction of Defnalone with Other Drugs

Defnalone should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Ketoconazole

Carbamazepine

Rifampicin

Leflunomide

Dexamethasone

Typhoid-Ty 21a Vaccine

Typhoid-Ty 21a Vaccine

Moderate

Defnalone Contraindications

If you are suffering from any of the following diseases, you should not take Defnalone unless your doctor advises you to do so -

Allergy
Diabetes
Heart Disease
Kidney Disease
Peptic Ulcer
Myasthenia Gravis

Frequently asked Questions about Defnalone

Is this Defnalone habit forming or addictive?

Forming a habit of Defnalone has not been reported.

No
Is it safe to drive or operate heavy machinery when consuming?

Defnalone will not make you feel sleepy or drowsy. So you drive or operate machinery safely.

Safe
Is it safe?

Defnalone is safe but it is important to consult a doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

There is no benefit of taking Defnalone for mental disorders.

No

Defnalone Interactions with Food and Alcohol

Interaction between Food and Defnalone

Due to the absence of research, it is difficult to say how Defnalone and food will interact.

Unknown
Interaction between Alcohol and Defnalone

Due to lack of research, there is no information about the side effects of taking Defnalone with alcohol.

Unknown

Frequently asked Questions about Defnalone

Question about 6 years ago

What is Defnalone?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

Defnalone is a brand name of deflazacort. It is a prescription drug that belongs to the class of drugs called steroids (corticosteroid). It is used for the treatment of Duchenne muscular dystrophy which is a progressive disease in which the muscles do not function properly in adults and in children 5 years of age and older.

Question over 5 years ago

Can I take Defnalone without consulting a doctor?

Dr. Vedprakash Verma MBBS, MD , Cardiology

No, Defnalone is a prescription drug so do not take it without consulting a doctor. It can be harmful for the patient to take this medicine without a doctor's recommendation because it suppresses the immune system that causes low immunity. Low immunity can further lead to multiple infections of bacterial and viral origins.

Question over 5 years ago

Does [Medicne] cause low potassium?

Dr. Ram Saini MD, MBBS , General Physician

Yes, only if Defnalone is taken along with any one of these drugs which are bumetanide, ethacrynic acid, furosemide, and torsemide then it may lead to low potassium levels in the blood. Taking this medicine with one of these drugs can result in increased loss of potassium from your body. It is recommended to avoid these medicines if you are taking Defnalone.

Question over 5 years ago

Is Defnalone more effective than prednisolone in diabetic patients?

Dr. Ashish Mishra MBBS , Pathology

Yes, Defnalone have been reported to be more effective than prednisolone in people with diabetes.

Question almost 6 years ago

How does Defnalone work?

Dr. R.K Singh MBBS , Diabetology

Defnalone works by suppressing body's normal immune response to inflammation (swelling). This results in reduced inflammation (swelling) and provides relief from the symptoms associated with the Duchenne muscular dystrophy.