Capebel DT contains Capecitabine, an oral prodrug of 5-fluorouracil (5-FU), used in the treatment of various cancers. Capecitabine is designed to selectively activate in tumor tissues, reducing systemic side effects and enhancing therapeutic efficacy.
Composition:
Active Ingredient: Capecitabine 500 mg.
Form: Film-coated tablet.
Route of Administration: Oral.
Indications:
Colorectal Cancer:
Treatment for metastatic colorectal cancer.
Adjuvant therapy for patients with Dukes' C colon cancer after surgery.
Breast Cancer:
Treatment of locally advanced or metastatic breast cancer.
Commonly used in combination with docetaxel after anthracycline-based chemotherapy failure.
Gastric Cancer:
Used in advanced gastric cancer, often in combination with platinum-based regimens.
Off-Label Uses:
Sometimes prescribed for other solid tumors under clinical discretion.
Mechanism of Action:
Capecitabine is converted enzymatically into 5-fluorouracil (5-FU) within tumor cells. The active metabolite interferes with DNA synthesis by:
Inhibiting thymidylate synthase, which blocks thymidine production needed for DNA replication.
Disrupting RNA and protein synthesis, ultimately leading to cancer cell death.
This tumor-selective activation minimizes systemic toxicity.
Capebel DT is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
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| Geriatric |
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| Adult(Female) |
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Based on research, the following side effects have been observed when Capebel DT is used -
Moderate
Mild
Is the use of Capebel DT safe for pregnant women?
Capebel DT should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.
Is the use of Capebel DT safe during breastfeeding?
Women who are breastfeeding may experience severe harmful effects after taking Capebel DT. It should only be taken after medical advice.
What is the effect of Capebel DT on the Kidneys?
Kidney can be affected by Capebel DT. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.
What is the effect of Capebel DT on the Liver?
There may be an adverse effect on the liver after taking Capebel DT. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.
What is the effect of Capebel DT on the Heart?
Very few cases of side effects of Capebel DT on the heart have been reported.
Capebel DT should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Capebel DT unless your doctor advises you to do so -
Is this Capebel DT habit forming or addictive?
Forming a habit of Capebel DT has not been reported.
Is it safe to drive or operate heavy machinery when consuming?
You may feel sleepy or tired after taking Capebel DT. So it is best to avoid driving.
Is it safe?
Capebel DT is safe but it is important to consult a doctor before taking it.
Is it able to treat mental disorders?
There is no benefit of taking Capebel DT for mental disorders.
Interaction between Food and Capebel DT
Taking Capebel DT with food does not harm your health.
Interaction between Alcohol and Capebel DT
No research has been done on this till date. Therefore, it is not known what the effect of taking Capebel DT with alcohol will be.
This medicine data has been created by -
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 272-273
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 864
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Xeloda® (capecitabine)
Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Capecitabine Sandoz® (capecitabine)