Bryxta 300mg Injection

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12ml Injection in 1 Vial Out of Stock
₹ 28995
12ml Injection 1 Vial ₹ 28995
  • Out of Stock

  • Manufactured by: Zydus Cadila
  • Contains / Salt: Bevacizumab

Bryxta 300mg Injection

12ml Injection in 1 Vial
₹ 28995
12ml Injection | 1 Vial
₹ 28995
0 people have bought this recently
  • Manufactured by: Zydus Cadila
  • Contains / Salt: Bevacizumab

Bryxta 300mg Injection Information

Bryxta is a monoclonal antibody used in the treatment of various cancers. It works by inhibiting angiogenesis, the process by which tumors develop new blood vessels to sustain their growth. Bryxta specifically binds to vascular endothelial growth factor (VEGF), a protein that promotes the formation of new blood vessels. By neutralizing VEGF, Bryxta starves tumors of their blood supply, inhibiting growth and progression. 

Indications:

  • Colorectal Cancer: Advanced or metastatic stages, often in combination with chemotherapy.
  • Non-Small Cell Lung Cancer (NSCLC): Metastatic cases, in combination with chemotherapy.
  • Renal Cell Carcinoma (RCC): Advanced stages, often combined with interferon alfa.
  • Cervical Cancer: Persistent, recurrent, or metastatic cases.
  • Glioblastoma: As a second-line treatment.
  • Ovarian Cancer: Platinum-resistant and recurrent forms.

Bryxta is a cornerstone in targeted cancer therapy due to its innovative approach to halting tumor growth. However, its use requires careful consideration of patient-specific factors and potential side effects. Collaborating with oncologists and monitoring during treatment ensures the best outcomes for patients.

Side Effects: Hypertension (high blood pressure), Fatigue, Nausea and vomiting, Nosebleeds, Proteinuria (protein in the urine), 

Severe side effects: Gastrointestinal perforations, Hemorrhage, Arterial thromboembolism, Nephrotic syndrome.

Contraindications

  • Hypersensitivity to Bryxta or its components
  • Active infections or significant recent surgical procedures
  • Uncontrolled hypertension

Precautions

  • Pregnancy and Lactation: Bryxta may harm the fetus; effective contraception is advised during and after treatment.
  • Wound Healing: Therapy should be delayed in patients undergoing major surgery.
  • Monitoring: Regular monitoring of blood pressure, kidney function, and signs of bleeding is essential.

Formulation: Bryxta is available as an intravenous infusion.

Typical Dosing: Colorectal Cancer: 5-10 mg/kg every 2 weeks.

NSCLC: 15 mg/kg every 3 weeks.

Dosage varies based on the cancer type, patient condition, and combination regimen.

Storage and Handling

  • Store Bryxta vials at 2°C to 8°C (36°F to 46°F).
  • Do not freeze or shake the vials.
  • Use the prepared solution immediately or within the recommended timeframe.


Bryxta 300mg Injection Benefits & Uses

Bryxta 300mg Injection is used to treat the following -

Other Benefits

Bryxta 300mg Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Kidney Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Ovarian Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Kidney Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor


Bryxta 300mg Injection Side Effects

Based on research, the following side effects have been observed when Bryxta 300mg Injection is used -

Severe

Moderate

Mild

Common

Unknown

Bryxta 300mg Injection Related Warnings

  • Is the use of Bryxta 300mg Injection safe for pregnant women?


    Pregnant women may get severe side effects after taking Bryxta. If you are pregnant, do not take Bryxta without a doctor's advice.

    Severe
  • Is the use of Bryxta 300mg Injection safe during breastfeeding?


    Bryxta should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Bryxta 300mg Injection on the Kidneys?


    Bryxta may cause harmful effects on kidney. if you feel its having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Bryxta 300mg Injection on the Liver?


    The liver can be affected by Bryxta. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Bryxta only after medical advice.

    Moderate
  • What is the effect of Bryxta 300mg Injection on the Heart?


    Bryxta can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate


Severe Interaction of Bryxta 300mg Injection with Other Drugs

Bryxta 300mg Injection should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Bryxta 300mg Injection Contraindications

If you are suffering from any of the following diseases, you should not take Bryxta 300mg Injection unless your doctor advises you to do so -



Frequently asked Questions about Bryxta 300mg Injection

  • Is this Bryxta 300mg Injection habit forming or addictive?


    Bryxta 300mg Injection is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    You may feel sleepy or tired after taking Bryxta 300mg Injection. So it is best to avoid driving.

    Dangerous
  • Is it safe?


    Yes, but take Bryxta 300mg Injection only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Bryxta 300mg Injection for mental disorders.

    No

Bryxta 300mg Injection Interactions with Food and Alcohol

  • Interaction between Food and Bryxta 300mg Injection


    You can take Bryxta 300mg Injection with food.

    Safe
  • Interaction between Alcohol and Bryxta 300mg Injection


    No research has been done on this till date. Therefore, it is not known what the effect of taking Bryxta 300mg Injection with alcohol will be.

    Unknown


See all substitutes for Bryxta



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



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