Halsbev 400mg Injection

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1 Injection in 1 Vial Out of Stock
₹ 55000
1 Injection 1 Vial ₹ 55000
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Halsbev 400mg Injection

1 Injection in 1 Vial
₹ 55000
1 Injection | 1 Vial
₹ 55000
0 people have bought this recently

Halsbev 400mg Injection Information

Halsbev is a monoclonal antibody used in the treatment of various cancers. It works by inhibiting angiogenesis, the process by which tumors develop new blood vessels to sustain their growth. Halsbev specifically binds to vascular endothelial growth factor (VEGF), a protein that promotes the formation of new blood vessels. By neutralizing VEGF, Halsbev starves tumors of their blood supply, inhibiting growth and progression. 

Indications:

  • Colorectal Cancer: Advanced or metastatic stages, often in combination with chemotherapy.
  • Non-Small Cell Lung Cancer (NSCLC): Metastatic cases, in combination with chemotherapy.
  • Renal Cell Carcinoma (RCC): Advanced stages, often combined with interferon alfa.
  • Cervical Cancer: Persistent, recurrent, or metastatic cases.
  • Glioblastoma: As a second-line treatment.
  • Ovarian Cancer: Platinum-resistant and recurrent forms.

Halsbev is a cornerstone in targeted cancer therapy due to its innovative approach to halting tumor growth. However, its use requires careful consideration of patient-specific factors and potential side effects. Collaborating with oncologists and monitoring during treatment ensures the best outcomes for patients.

Side Effects: Hypertension (high blood pressure), Fatigue, Nausea and vomiting, Nosebleeds, Proteinuria (protein in the urine), 

Severe side effects: Gastrointestinal perforations, Hemorrhage, Arterial thromboembolism, Nephrotic syndrome.

Contraindications

  • Hypersensitivity to Halsbev or its components
  • Active infections or significant recent surgical procedures
  • Uncontrolled hypertension

Precautions

  • Pregnancy and Lactation: Halsbev may harm the fetus; effective contraception is advised during and after treatment.
  • Wound Healing: Therapy should be delayed in patients undergoing major surgery.
  • Monitoring: Regular monitoring of blood pressure, kidney function, and signs of bleeding is essential.

Formulation: Halsbev is available as an intravenous infusion.

Typical Dosing: Colorectal Cancer: 5-10 mg/kg every 2 weeks.

NSCLC: 15 mg/kg every 3 weeks.

Dosage varies based on the cancer type, patient condition, and combination regimen.

Storage and Handling

  • Store Halsbev vials at 2°C to 8°C (36°F to 46°F).
  • Do not freeze or shake the vials.
  • Use the prepared solution immediately or within the recommended timeframe.


Halsbev 400mg Injection Benefits & Uses

Halsbev 400mg Injection is used to treat the following -

Main Benefits

Other Benefits

Halsbev 400mg Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Kidney Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Ovarian Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Kidney Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Halsbev 400mg Injection Related Warnings

  • Is the use of Halsbev 400mg Injection safe for pregnant women?


    Halsbev can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Halsbev 400mg Injection safe during breastfeeding?


    Taking Halsbev may lead to serious side effects if you are breastfeeding. Halsbev should not be taken by breastfeeding women unless prescribed by the doctor.

    Severe
  • What is the effect of Halsbev 400mg Injection on the Kidneys?


    Halsbev can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Halsbev 400mg Injection on the Liver?


    The liver can be affected by Halsbev. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Halsbev only after medical advice.

    Moderate
  • What is the effect of Halsbev 400mg Injection on the Heart?


    You may experience side effects on your heart after taking Halsbev. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.

    Moderate


Severe Interaction of Halsbev 400mg Injection with Other Drugs

Halsbev 400mg Injection should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Halsbev 400mg Injection Contraindications

If you are suffering from any of the following diseases, you should not take Halsbev 400mg Injection unless your doctor advises you to do so -



Frequently asked Questions about Halsbev 400mg Injection

  • Is this Halsbev 400mg Injection habit forming or addictive?


    Halsbev 400mg Injection is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Halsbev 400mg Injection can make you feel drowsy.

    Dangerous
  • Is it safe?


    Yes, but take Halsbev 400mg Injection only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Halsbev 400mg Injection cannot treat any kind of mental disorder.

    No

Halsbev 400mg Injection Interactions with Food and Alcohol

  • Interaction between Food and Halsbev 400mg Injection


    Taking Halsbev 400mg Injection with food is safe.

    Safe
  • Interaction between Alcohol and Halsbev 400mg Injection


    Information about the interaction of Halsbev 400mg Injection and alcohol is not currently available because this topic has not been researched yet.

    Unknown


See all substitutes for Halsbev



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 224-225

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 871

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Avastin® (bevacizumab)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Avastin® (bevacizumab)



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