Borviz T

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Borviz T Information

Borviz T is an antineoplastic (anti-cancer) medication that belongs to the class of proteasome inhibitors. It is primarily used for the treatment of multiple myeloma and mantle cell lymphoma. By disrupting cellular processes, it helps to prevent cancer cells from growing and multiplying.

Uses

Multiple MyelomaBorviz T  is often used as a first-line treatment in combination with other drugs such as dexamethasone or lenalidomide.

Mantle Cell Lymphoma (MCL): It is approved for the treatment of MCL in patients who have received at least one prior therapy.

Borviz T inhibits the 26S proteasome, a protein complex involved in breaking down unneeded or damaged proteins. By inhibiting the proteasome, Borviz T induces apoptosis (programmed cell death) in cancer cells, disrupting their survival mechanisms.


Borviz T Benefits & Uses

Borviz T is used to treat the following -

Main Benefits

Other Benefits

Borviz T Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Multiple Myeloma
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: 2 weeks
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Multiple Myeloma
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: 2 weeks
  • Special Instructions: As prescribed by the doctor

Borviz T Side Effects

Based on research, the following side effects have been observed when Borviz T is used -

Severe

Moderate

  • Bone Pain
  • Orthostatic Hypotension (Sudden Lowering of Blood Pressure on Standing)

Mild

Borviz T Related Warnings

  • Is the use of Borviz T safe for pregnant women?


    Borviz T can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Borviz T safe during breastfeeding?


    Borviz T should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Borviz T on the Kidneys?


    Using Borviz T does not have any harmful effects on kidneys.

    Safe
  • What is the effect of Borviz T on the Liver?


    There may be an adverse effect on the liver after taking Borviz T. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Borviz T on the Heart?


    The heart can be affected by Borviz T. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

    Moderate

Severe Interaction of Borviz T with Other Drugs

Borviz T should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Borviz T Contraindications

If you are suffering from any of the following diseases, you should not take Borviz T unless your doctor advises you to do so -


Frequently asked Questions about Borviz T

  • Is this Borviz T habit forming or addictive?


    Borviz T does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Borviz T you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Yes, but take Borviz T only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Borviz T is not used to treat mental disorders.

    No

Borviz T Interactions with Food and Alcohol

  • Interaction between Food and Borviz T


    When consumed with certain foods, Borviz T may take longer to have an effect. Contact your doctor about this.

    Mild
  • Interaction between Alcohol and Borviz T


    Information about the interaction of Borviz T and alcohol is not currently available because this topic has not been researched yet.

    Unknown

See all substitutes for Borviz T


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 234-235

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 871

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Velcade® (bortezomib)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Bortezomib Aft (Bortezomib)


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