Bortirel

  people have bought this recently
1 Injection in 1 Vial Out of Stock
₹ 4896.66
1 Injection 1 Vial ₹ 4896.66

Bortirel Information

Bortirel is an antineoplastic (anti-cancer) medication that belongs to the class of proteasome inhibitors. It is primarily used for the treatment of multiple myeloma and mantle cell lymphoma. By disrupting cellular processes, it helps to prevent cancer cells from growing and multiplying.

Uses

Multiple MyelomaBortirel is often used as a first-line treatment in combination with other drugs such as dexamethasone or lenalidomide.

Mantle Cell Lymphoma (MCL): It is approved for the treatment of MCL in patients who have received at least one prior therapy.

Bortirel inhibits the 26S proteasome, a protein complex involved in breaking down unneeded or damaged proteins. By inhibiting the proteasome, Bortirel induces apoptosis (programmed cell death) in cancer cells, disrupting their survival mechanisms.


Bortirel Benefits & Uses

Bortirel is used to treat the following -

Main Benefits

Other Benefits

Bortirel Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Multiple Myeloma
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: 2 weeks
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Multiple Myeloma
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: 2 weeks
  • Special Instructions: As prescribed by the doctor

Bortirel Side Effects

Based on research, the following side effects have been observed when Bortirel is used -

Severe

Moderate

  • Bone Pain
  • Orthostatic Hypotension (Sudden Lowering of Blood Pressure on Standing)

Mild

Bortirel Related Warnings

  • Is the use of Bortirel safe for pregnant women?


    Bortirel can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Bortirel safe during breastfeeding?


    Women who are breastfeeding may experience severe harmful effects after taking Bortirel. It should only be taken after medical advice.

    Severe
  • What is the effect of Bortirel on the Kidneys?


    There are no side effects of Bortirel on the kidneys.

    Safe
  • What is the effect of Bortirel on the Liver?


    Bortirel may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Bortirel on the Heart?


    Bortirel can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate

Severe Interaction of Bortirel with Other Drugs

Bortirel should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Bortirel Contraindications

If you are suffering from any of the following diseases, you should not take Bortirel unless your doctor advises you to do so -


Frequently asked Questions about Bortirel

  • Is this Bortirel habit forming or addictive?


    Bortirel is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    You may feel sleepy or tired after taking Bortirel. So it is best to avoid driving.

    Dangerous
  • Is it safe?


    Yes, Bortirel is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Bortirel cannot treat any kind of mental disorder.

    No

Bortirel Interactions with Food and Alcohol

  • Interaction between Food and Bortirel


    Some foods when eaten with Bortirel can alter the onset of actions. Discuss this with your doctor.

    Mild
  • Interaction between Alcohol and Bortirel


    It is difficult to say anything about the effect of Bortirel and alcohol. No research has been done on this yet.

    Unknown

See all substitutes for Bortirel


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 234-235

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 871

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Velcade® (bortezomib)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Bortezomib Aft (Bortezomib)


In stock alternatives of Bortirel (based on Bortezomib)

CHEMOBORT 2MG INJECTION ₹854 122030% off
Bortecad 2 mg Injection 1 Injection in 1 Packet ₹15201 152010% off
Bortenat 2 Injection 1 Injection in 1 Packet ₹11300 113000% off
Borviz 2 Injection 1 Injection in 1 Packet ₹3389 33890% off
Borzomed 3.5mg Injection 1 Injection in 1 Vial ₹6120 61200% off
Bortezest 3.5mg Injection 1 Injection in 1 Vial ₹20000 200000% off

BEST ALTERNATIVE
₹512 ₹995 48% OFF Save: ₹483
Multivitamin Capsules