Bortero

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Bortero Information

Bortero is an antineoplastic (anti-cancer) medication that belongs to the class of proteasome inhibitors. It is primarily used for the treatment of multiple myeloma and mantle cell lymphoma. By disrupting cellular processes, it helps to prevent cancer cells from growing and multiplying.

Uses

Multiple MyelomaBortero is often used as a first-line treatment in combination with other drugs such as dexamethasone or lenalidomide.

Mantle Cell Lymphoma (MCL): It is approved for the treatment of MCL in patients who have received at least one prior therapy.

Bortero inhibits the 26S proteasome, a protein complex involved in breaking down unneeded or damaged proteins. By inhibiting the proteasome, Bortero induces apoptosis (programmed cell death) in cancer cells, disrupting their survival mechanisms.


Bortero Benefits & Uses

Bortero is used to treat the following -

Main Benefits

Other Benefits

Bortero Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Multiple Myeloma
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: 2 weeks
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Multiple Myeloma
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: 2 weeks
  • Special Instructions: As prescribed by the doctor

Bortero Side Effects

Based on research, the following side effects have been observed when Bortero is used -

Severe

Moderate

  • Bone Pain
  • Orthostatic Hypotension (Sudden Lowering of Blood Pressure on Standing)

Mild

Bortero Related Warnings

  • Is the use of Bortero safe for pregnant women?


    Bortero has many dangerous side effects in pregnant women. If you are pregnant, do not consume Bortero without medical advice.

    Severe
  • Is the use of Bortero safe during breastfeeding?


    Bortero may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

    Severe
  • What is the effect of Bortero on the Kidneys?


    Bortero is not harmful for kidneys.

    Safe
  • What is the effect of Bortero on the Liver?


    Bortero can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Bortero on the Heart?


    Bortero may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate

Severe Interaction of Bortero with Other Drugs

Bortero should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Bortero Contraindications

If you are suffering from any of the following diseases, you should not take Bortero unless your doctor advises you to do so -


Frequently asked Questions about Bortero

  • Is this Bortero habit forming or addictive?


    Bortero does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Bortero as you may feel sleepy.

    Dangerous
  • Is it safe?


    Yes, but take Bortero only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Bortero cannot treat any kind of mental disorder.

    No

Bortero Interactions with Food and Alcohol

  • Interaction between Food and Bortero


    When consumed with certain foods, Bortero may take longer to have an effect. Contact your doctor about this.

    Mild
  • Interaction between Alcohol and Bortero


    Information about the interaction of Bortero and alcohol is not currently available because this topic has not been researched yet.

    Unknown

See all substitutes for Bortero


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 234-235

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 871

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Velcade® (bortezomib)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Bortezomib Aft (Bortezomib)


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