Janumet 50/500 Tablet

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15 Tablet in 1 Strip
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15 TABLET 1 Strip ₹ 361 ₹380 5% OFF Save: ₹19
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Istamet 50 Mg/500 Mg Tablet (15)
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Janumet 50/500 Tablet

15 Tablet in 1 Strip
₹ 361 ₹380 5% OFF Save: ₹19
15 TABLET | 1 Strip
₹ 361 ₹380 5% OFF Save: ₹19
3067 people have bought this recently
myUpchar Recommended - 58% more Savings
Istamet 50 Mg/500 Mg Tablet (15)
Istamet 50 Mg/500 Mg Tablet (15) 15 Tablet in 1 Strip ₹148.2 ₹1565% off  BUY NOW
myUpchar Recommended - 58% more Savings over Janumet 50/500 Tablet
Istamet 50 Mg/500 Mg Tablet (15)
Istamet 50 Mg/500 Mg Tablet (15) 15 Tablet in 1 Strip ₹148.2 ₹1565% off  BUY NOW

Janumet 50/500 Tablet Information

Janumet 50/500 Tablet is a prescription medicine that is available as a Tablet. Diabetes are some of its major therapeutic uses. Janumet 50/500 Tablet also has some secondary and off-label uses. These are listed below.

Medical history of the patient along with age and gender determines the dosage of Janumet 50/500 Tablet. The condition it has been prescribed for, and the route of administration also determine the right dosage. Detailed information has been provided in the dosage section.

The most common side effects of Janumet 50/500 Tablet are Nausea or vomiting, Headache, Diarrhoea. While these are the most often observed Janumet 50/500 Tablet side effects, there are can be others also. These have been listed below. Such side effects of Janumet 50/500 Tablet normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.

Janumet 50/500 Tablet's effect during pregnancy is Mild and Safe while nursing. It is important to know if Janumet 50/500 Tablet has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Janumet 50/500 Tablet related warnings section.

Janumet 50/500 Tablet is not recommended if you suffer from certain medical conditions as it can have adverse effects. Pancreatitis are examples of such conditions. Other conditions have been mentioned below in the Janumet 50/500 Tablet contraindications section.

Additionally, Janumet 50/500 Tablet may also adversely react with other medicines. Refer to the list below for further details.

Along with the above-mentioned precautions, remember that taking Janumet 50/500 Tablet is considered not safe while driving, and is not addictive.



Janumet 50/500 Tablet Benefits & Uses

Janumet 50/500 Tablet is used to treat the following -

Main Benefits

Other Benefits

  • Diabetes Type 2

Janumet 50/500 Tablet Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 50 mg sitagliptin and 500 mg metformin
Geriatric
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 50 mg sitagliptin and 500 mg metformin

Janumet 50/500 Tablet Related Warnings

  • Is the use of Janumet 50/500 Tablet safe for pregnant women?


    Janumet has mild to no side effects in pregnant women.

    Mild
  • Is the use of Janumet 50/500 Tablet safe during breastfeeding?


    Janumet is completely safe for breastfeeding women.

    Safe
  • What is the effect of Janumet 50/500 Tablet on the Kidneys?


    Janumet may cause harmful effects on kidney. if you feel its having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Janumet 50/500 Tablet on the Liver?


    Using Janumet does not have any harmful effects on the liver.

    Safe
  • What is the effect of Janumet 50/500 Tablet on the Heart?


    Information about safety of Janumet for heart is not available since scientific research on this is yet to be done.

    Unknown


Janumet 50/500 Tablet Contraindications

If you are suffering from any of the following diseases, you should not take Janumet 50/500 Tablet unless your doctor advises you to do so -



Frequently asked Questions about Janumet 50/500 Tablet

  • Is this Janumet 50/500 Tablet habit forming or addictive?


    No, there is no any evidence that Janumet 50/500 Tablet is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Janumet 50/500 Tablet you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Janumet 50/500 Tablet is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Janumet 50/500 Tablet in mental disorders is not effective.

    No

Janumet 50/500 Tablet Interactions with Food and Alcohol

  • Interaction between Food and Janumet 50/500 Tablet


    Due to the absence of research, it is difficult to say how Janumet 50/500 Tablet and food will interact.

    Unknown
  • Interaction between Alcohol and Janumet 50/500 Tablet


    No research has been done on this till date. Therefore, it is not known what the effect of taking Janumet 50/500 Tablet with alcohol will be.

    Unknown


Frequently asked Questions about Janumet 50/500 Tablet

Question almost 6 years ago

How does Janumet work?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Janumet works by decreasing the hepatic glucose production. It also works to lower blood sugar by increasing your sensitivity to insulin and decreasing the amount of glucose that is absorbed from the food you eat.

Question over 5 years ago

Does Janumet cause sleep problems?

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Yes, Janumet can cause some sleep problems, especially insomnia. On the other hand, Janumet has proven to be useful for preventing sleep apnea. The exact relationship between Janumet and sleep problems is still not clear, and further studies are needed for a clearer understanding.

Question over 5 years ago

How long should I take Janumet for?

Dr. Ram Saini MD, MBBS , General Physician

Janumet can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime. 

Question about 5 years ago

How does Janumet increase lactic acidosis?

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Janumet treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Janumet induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Question over 5 years ago

Can I take Janumet with statin?

Dr. R.K Singh MBBS , Diabetology

Yes, Janumet can be taken with the statin. There is no serious or harmful interaction have been observed between them. Some studies say that it's possible your blood sugar (blood glucose) level may increase when you take a statin, which may lead to developing type 2 diabetes. The risk is small but important enough that the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes.



See all substitutes for Janumet



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Januvia® (sitagliptin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 274-275

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1143-1144

EPAR summary for the public [Internet]: Janumet sitagliptin / metformin hydrochloride. EMA/370017/2013 EMEA/H/C/000861

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