Dr. Bharat MBBS , General Physician

The long-term use can lead to the deficiency of Vitamin B12, which can further lead to megaloblastic anemia. Furthermore, Long-term Metformin use can also lead to kidney and liver problems. 

Dr. Ramraj MBBS , Other

Yes, Lupisit M Tablet can cause low blood sugar (hypoglycemia). However, this can also occur if you delay or miss a meal, drink alcohol, exercise more than usual, can't eat due to stomach upset, and taking other antidiabetic medicine with metformin. So, regular monitoring of blood glucose level is needed and be cautious of symptoms of hypoglycemia, always keep glucose-rich food with you. 

Dr. Sameer Awadhiya MBBS , Pediatrics

Yes, you can take Lupisit M Tablet with a beta-blocker. People with diabetes tend to develop heart disease or stroke at an earlier age than the general population. One reason for this is that high glucose levels increase your risk of high blood pressure (hypertension). No harmful interactions are seen between them. However, a recent study suggests that beta-blockers can decrease the plasma level of Lupisit M Tablet and long-term use can increase lactic acid and uric acid in the blood.

Dr. Joydeep Sarkar MBBS , Internal Medicine

Yes, Lupisit M Tablet can cause night sweat, the exact mechanism of sweating is not known. But some research suggests that Lupisit M Tablet causes hypoglycemia (low blood sugar) especially at night which can cause night sweats. Need to monitor your blood glucose level regularly, and talk to your doctor as your dose of Lupisit M Tablet may need to be adjusted.

Dr. Manju Shekhawat MBBS , General Physician

No, you should not take alcohol with Lupisit M Tablet, because it can cause serious side effects which includes hypoglycemia (low blood sugar). The risk of hypoglycemia is higher when you're drinking and taking Lupisit M Tablet than if you're just taking Lupisit M Tablet. Some of the signs of hypoglycemia include dizziness, confusion, and drowsiness.