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Topinate, a prescription drug, is manufactured in various forms such as Solution, Cream, Gel, Ointment. Primarily, it is used for the treatment of Psoriasis, Eczema, Dermatitis. Secondary and off-label uses of Topinate have also been mentioned below.
The optimal dosage of Topinate is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. For detailed information on this, read through the dosage section.
Some other side effects of Topinate have been listed ahead. Usually, these side effects of Topinate go away soon, and do not persist beyond the duration of the treatment. Consult your doctor if these side effects become worse or stay for a longer duration.
It is also important to note that Topinate has a Moderate effect for pregnant women and Mild effect on lactating mothers. Warnings related to Topinate's effects on the liver, heart and kidney, if any, have been listed below.
Other contraindications of Topinate have been discussed in the sections ahead.
Besides this, Topinate may also have severe interaction with some medicines. Refer to the list below for further details.
You should also be aware that Topinate is safe while driving, and is addiction.
Topinate is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
Is the use of Topinate safe for pregnant women?
Topinate may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Topinate again without your doctor's advice.
Is the use of Topinate safe during breastfeeding?
Topinate has been seen to have minimal side effects on breastfeeding women.
What is the effect of Topinate on the Kidneys?
There are no side effects of Topinate on the kidneys.
What is the effect of Topinate on the Liver?
There are no any side effects of Topinate on the liver.
What is the effect of Topinate on the Heart?
Topinate is completely safe for the heart.
Topinate should not be taken with following medicines due to severe side effects it may cause to patients -
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Topinate unless your doctor advises you to do so -
Is this Topinate habit forming or addictive?
No, there is no any evidence that Topinate is addictive.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can operate a vehicle or heavy machinery after taking Topinate since it does not cause drowsiness.
Is it safe?
Yes, but consume Topinate only on doctor's advice.
Is it able to treat mental disorders?
Topinate is unable to treat or cure mental disorders.
Interaction between Food and Topinate
There isn't any research available on the side effects of taking Topinate with food.
Interaction between Alcohol and Topinate
Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Topinate.
No, Topinate is a prescription drug, so do not use it without consulting a doctor. It can be harmful for the patient to use this medicine without a doctor's recommendation because it can cause unpleasant side effects. Hence, the patient should seek doctors advice before using this medication by himself or herself.
Yes, Topinate might lighten skin because it causes skin atrophy (skin thinning) which reduces the darkness of the skin. However, Topinate is not approved for skin lightening and should not be used for this purpose because it can cause unpleasant side effects.
Yes, Topinate may cause skin discoloration or color changes. It is a rare side effect of this drug. However, the exact cause behind skin discoloration is not known but it is more likely to occur if the skin is covered with a dressing after applying this drug. So you are advised to not cover your skin with a dressing after applying this drug.
Application of Topinate on the face must be avoided but if it has been advised by your doctor then you can use it only for a short-term period not more than 5 days because the skin on your face thins easily.
Yes, Topinate might be used for the treatment of lichen sclerosus (LS) which is a skin condition that causes thinning of the skin and white patches, generally in the genital area. Clinical studies have found Topinate to be effective in the treatment of lichen sclerosus (LS).
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Impoyz (clobetasol propionate)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 895
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 369-370