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Pacitane, a prescription drug, is manufactured in various forms such as Tablet. It is primarily used for the treatment of Parkinson's Disease.
Medical history of the patient along with age and gender determines the dosage of Pacitane. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.
The most common side effects of Pacitane are Dry Mouth, Nausea or vomiting. Some other side effects of Pacitane have been listed ahead. These side effects of Pacitane are usually temporary and subside with the completion of treatment. If, however, they worsen or do not go away, please speak with your physician.
It is also important to note that Pacitane has a Moderate effect for pregnant women and Severe effect on lactating mothers. In addition, Pacitane's effects on the liver, heart and kidney are discussed below in the Pacitane related warnings section.
Pacitane is contraindicated in people with pre-existing medical conditions like High BP (High Blood Pressure) as it can result in adverse effects. Other contraindications of Pacitane have been discussed in the sections ahead.
Drug interactions for Pacitane have been reported in the medical literature. Refer to the list below for further details.
In addition to these precautions, you may also note that Pacitane is not safe while driving, and is is not addictive in nature.
Pacitane is used to treat the following -
Main Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Is the use of Pacitane safe for pregnant women?
Pacitane may have some side effects during pregnancy. Pregnant women should discontinue the use of Pacitane, and talk to their doctor, if they notice any discomfort.
Is the use of Pacitane safe during breastfeeding?
Pacitane may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.
What is the effect of Pacitane on the Kidneys?
Very few cases of side effects of Pacitane on kidney have been reported.
What is the effect of Pacitane on the Liver?
Pacitane is rarely harmful for the liver.
What is the effect of Pacitane on the Heart?
There are no any side effects of Pacitane for the heart.
Pacitane should not be taken with following medicines due to severe side effects it may cause to patients -
Moderate
If you are suffering from any of the following diseases, you should not take Pacitane unless your doctor advises you to do so -
Is this Pacitane habit forming or addictive?
Pacitane does not cause addiction.
Is it safe to drive or operate heavy machinery when consuming?
After taking Pacitane, you should not drive or work on any heavy machine, as Pacitane can make you drowsy.
Is it safe?
Pacitane should be used only after doctor's advice.
Is it able to treat mental disorders?
Yes, taking Pacitane can treat mental disorders.
Interaction between Food and Pacitane
Taking Pacitane with food does not harm your health.
Interaction between Alcohol and Pacitane
Consuming Pacitane with alcohol can have many serious effects on your body.
Usually, in starting of the treatment Pacitane is given once a day then its dosage is gradually increased as per the need. You are advised to take it as prescribed by your doctor. It can be taken with or without food but if you experience stomach upset then take it with food. Precautions must be taken in patients with high blood pressure (hypertension), heart disease, and improper liver or kidney function.
Yes, Pacitane is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug at regular such as stomach upset, dizziness, and rash. However, if you experience any discomfort after taking this medicine then inform your doctor immediately and follow his/her instructions.
No, Pacitane is not a benzo (benzodiazepine). It belongs to the class of drugs known as the anticholinergics which is used to treat symptoms of Parkinson's disease and drug-induced abnormal movements.
No, Pacitane does not cause weight gain. In fact, it has been reported that Pacitane causes weight loss in children.
Pacitane contains trihexyphenidyl which is an anticholinergic drug that works through correcting the chemical imbalance in the brain by blocking the action of a chemical messenger (neurotransmitter acetylcholine). Blockage of acetylcholine actions results in relaxation of smooth muscles which helps in improving the muscle control and reducing stiffness. In this way, Pacitane provides relief to the patient from the symptoms of parkinsonism.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 433
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Trihexyphenidyl Hydrochloride (trihexyphenidyl hydrochloride)
Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Artane (trihexyphenidyl hydrochloride)