V-Strant 250mg Injection 2's

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5ml Injection in 1 Pre-filled Syringe
₹ 23500.47
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V-Strant 250mg Injection 2's

5ml Injection in 1 Pre-filled Syringe
₹ 23500
5ml Injection | 1 Pre-filled Syringe
₹ 23500
people have bought this recently

V-Strant 250mg Injection 2's Information

V-Strant contains Fulvestrant, a selective estrogen receptor degrader (SERD) used to treat hormone receptor-positive breast cancer in postmenopausal women. It works by binding to estrogen receptors, resulting in their degradation, which prevents estrogen from stimulating tumor growth.

Uses

Breast Cancer (HR-positive):

  • Treatment of estrogen receptor-positive, HER2-negative breast cancer in postmenopausal women who have progressed on anti-estrogen therapy like tamoxifen.

Combination with Other Drugs:

  • Used in combination with other therapies for advanced or metastatic breast cancer.

Fulvestrant binds to estrogen receptors on cancer cells, leading to their degradation. This prevents the estrogen receptor from activating genes responsible for cancer cell growth and proliferation.

Onset of Action

  • Fulvestrant begins to show therapeutic effects within 2-3 weeks after the first dose.

Duration of Action

  • The duration of action can last for several weeks, with periodic doses typically administered every 4 weeks.

Dosage

  • Initial Dose: 500 mg (administered as two 250 mg injections) on Day 1 and Day 15.
  • Maintenance Dose: 500 mg administered once a month (every 4 weeks) thereafter.

Common Side Effects

  • Injection site reactions (pain, redness, swelling)
  • Hot flashes
  • Nausea
  • Fatigue
  • Headache
  • Musculoskeletal pain
  • Liver enzyme abnormalities (elevated liver function tests)

Precautions

  • Liver Impairment: Use cautiously in patients with liver disease.
  • Monitor for signs of thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism).
  • Not recommended during pregnancy or breastfeeding.

Drug Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole): Can increase Fulvestrant levels.
  • CYP3A4 inducers (e.g., rifampin): May decrease Fulvestrant levels.
  • Warfarin: Regular monitoring of INR is recommended when used with Fulvestrant.

Storage

  • Store at room temperature (20-25°C). Do not freeze.


V-Strant 250mg Injection 2's Benefits & Uses

V-Strant 250mg Injection 2's is used to treat the following -

Main Benefits

V-Strant 250mg Injection 2's Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult(Female)
  • Disease: Breast Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 500 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Breast Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 500 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor


V-Strant 250mg Injection 2's Side Effects

Based on research, the following side effects have been observed when V-Strant 250mg Injection 2's is used -

Severe

Mild

  • Injection Site Allergic Reaction

Common

  • Urinary tract infection
  • Flu-like Symptoms

V-Strant 250mg Injection 2's Related Warnings

  • Is the use of V-Strant 250mg Injection 2's safe for pregnant women?


    Pregnant women may get severe side effects after taking V-Strant. If you are pregnant, do not take V-Strant without a doctor's advice.

    Severe
  • Is the use of V-Strant 250mg Injection 2's safe during breastfeeding?


    V-Strant may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking V-Strant, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of V-Strant.

    Moderate
  • What is the effect of V-Strant 250mg Injection 2's on the Kidneys?


    V-Strant may have mild side effects on the kidneys.

    Mild
  • What is the effect of V-Strant 250mg Injection 2's on the Liver?


    The liver can be affected by V-Strant. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart V-Strant only after medical advice.

    Moderate
  • What is the effect of V-Strant 250mg Injection 2's on the Heart?


    Very few cases of side effects of V-Strant on the heart have been reported.

    Mild


V-Strant 250mg Injection 2's Contraindications

If you are suffering from any of the following diseases, you should not take V-Strant 250mg Injection 2's unless your doctor advises you to do so -



Frequently asked Questions about V-Strant 250mg Injection 2's

  • Is this V-Strant 250mg Injection 2's habit forming or addictive?


    V-Strant 250mg Injection 2's does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    You may feel sleepy or tired after taking V-Strant 250mg Injection 2's. So it is best to avoid driving.

    Dangerous
  • Is it safe?


    Yes, V-Strant 250mg Injection 2's is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, V-Strant 250mg Injection 2's is not used to treat mental disorders.

    No

V-Strant 250mg Injection 2's Interactions with Food and Alcohol

  • Interaction between Food and V-Strant 250mg Injection 2's


    There isn't any research available on the side effects of taking V-Strant 250mg Injection 2's with food.

    Unknown
  • Interaction between Alcohol and V-Strant 250mg Injection 2's


    Information about the interaction of V-Strant 250mg Injection 2's and alcohol is not currently available because this topic has not been researched yet.

    Unknown


See all substitutes for V-Strant



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Faslodex® (fulvestrant)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 313



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₹23500
5ml Injection in 1 Pre-filled Syringe