Ruxolitinib Benefits & Uses

Ruxolitinib is used to treat the following -

Other Benefits

Polycythemia Vera

Ruxolitinib Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Primary Myelofibrosis Before or After Meal: Either Single Maximum Dose: 20 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 2 daily Course Duration: As directed by the doctor Special Instructions: Initial platelet count 100 to 200 x 10(9) cells/L can take 15 mg twice daily, 50 to 99 x 10(9) cells/L can take 5 mg twice daily
Geriatric	Disease: Primary Myelofibrosis Before or After Meal: Either Single Maximum Dose: 20 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 2 daily Course Duration: As directed by the doctor Special Instructions: Initial platelet count 100 to 200 x 10(9) cells/L can take 15 mg twice daily, 50 to 99 x 10(9) cells/L can take 5 mg twice daily

Ruxolitinib Side Effects

Based on research, the following side effects have been observed when Ruxolitinib is used -

Severe

Headache
Dizziness
Reduced blood platelets
Vertigo

Moderate

Edema
Hypertension
Constipation (Read More - Home remedies for constipation)

Mild

Diarrhoea
Fatigue

Common

Bruising or discoloration
Weight gain

Ruxolitinib Related Warnings

Is the use of Ruxolitinib safe for pregnant women?

No research has been done to ascertain the safety of Ruxolitinib in pregnant women. If you are pregnant, it is best to ask a doctor to know if you can take it.

Unknown
Is the use of Ruxolitinib safe during breastfeeding?

There is no research available on the side effects of Ruxolitinib in breastfeeding women. Therefore, its impact is unknown.

Unknown
What is the effect of Ruxolitinib on the Kidneys?

There may be some adverse effects on kidney after taking Ruxolitinib. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.

Moderate
What is the effect of Ruxolitinib on the Liver?

There may be an adverse effect on the liver after taking Ruxolitinib. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

Moderate
What is the effect of Ruxolitinib on the Heart?

Ruxolitinib may have mild side effects on the heart. Most people will never see any effect on the heart.

Mild

Severe Interaction of Ruxolitinib with Other Drugs

Ruxolitinib should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Clarithromycin

Indinavir

Itraconazole

Moderate

Carbamazepine

Ruxolitinib Contraindications

If you are suffering from any of the following diseases, you should not take Ruxolitinib unless your doctor advises you to do so -

Drug Allergy
Anemia
Fungal Infections
Liver Disease
Skin Cancer
Kidney Disease

Frequently asked Questions about Ruxolitinib

Is this Ruxolitinib habit forming or addictive?

No, there is no any evidence that Ruxolitinib is addictive.

No
Is it safe to drive or operate heavy machinery when consuming?

Ruxolitinib does not cause dizziness or sleep, so you can drive a vehicle or operate machinery also.

Safe
Is it safe?

Yes, but consume Ruxolitinib only on doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, Ruxolitinib cannot treat any kind of mental disorder.

No

Ruxolitinib Interactions with Food and Alcohol

Interaction between Food and Ruxolitinib

There isn't any research available on the side effects of taking Ruxolitinib with food.

Unknown
Interaction between Alcohol and Ruxolitinib

Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Ruxolitinib.

Unknown

See all substitutes for Ruxolitinib

Jakavi 15 Tablet - ₹56547
Jakavi 20 Tablet - ₹61367
Jakavi 5 Tablet - ₹27600
Ruxolitinib Tablet - ₹30084

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Jakafi™ (ruxolitinib)

Ruxolitinib Tablet