N-Zal Information

N-Zal, containing Enzalutamide as the active ingredient, is an oral medication used to treat certain types of prostate cancer. It is classified as an androgen receptor inhibitor and works by blocking the effects of androgens (male hormones) that promote the growth of cancer cells.

Uses:

Metastatic castration-resistant prostate cancer (mCRPC).
Non-metastatic castration-resistant prostate cancer (nmCRPC).
Metastatic hormone-sensitive prostate cancer (mHSPC).

Enzalutamide binds to androgen receptors on prostate cancer cells, preventing androgens like testosterone from activating these receptors. This inhibits the growth and survival of prostate cancer cells.

Dosage and Administration:

Typical dosage: 160 mg daily, taken as 4 capsules of 40 mg each.
Taken orally with or without food.
Dosage adjustments may be required for specific conditions or side effects.

Side Effects:
Common side effects:

Fatigue.
Hot flashes.
Weakness.
Back pain.
Hypertension (high blood pressure).

Serious side effects:

Seizures.
Risk of falls.
Heart issues like arrhythmias.

Precautions:

Regular monitoring of blood pressure and liver function is recommended.
Avoid in patients with a history of seizures or severe neurological conditions.
Not recommended for women, especially during pregnancy or breastfeeding.
Use with caution in elderly patients.

Drug Interactions:

Avoid concurrent use with strong CYP2C8 and CYP3A4 inhibitors or inducers.
Can interact with warfarin, antiepileptics, and other medications.

Storage Instructions:

Store at room temperature (20–25°C).
Keep away from moisture and direct sunlight.

N-Zal Benefits & Uses
N-Zal Dosage & How to Take
N-Zal Side Effects
N-Zal Related Warnings
Severe Interaction of N-Zal with Other Drugs
N-Zal Contraindications
Frequently asked Questions about N-Zal
N-Zal Interactions with Food and Alcohol

N-Zal Benefits & Uses

N-Zal is used to treat the following -

Main Benefits

Prostate Cancer

N-Zal Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Prostate Cancer Before or After Meal: Either Single Maximum Dose: 160 mg Dosage Form: Capsule Dosage Route: Oral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor
Geriatric	Disease: Prostate Cancer Before or After Meal: Either Single Maximum Dose: 160 mg Dosage Form: Capsule Dosage Route: Oral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor

N-Zal Side Effects

Based on research, the following side effects have been observed when N-Zal is used -

Severe

Fatigue
Musculoskeletal Pain (Bone, Muscle or Joint)
Headache

Moderate

Peripheral Edema
Hot Flashes
Back Pain (Read More - From Heat Therapy to Herbal Teas: Home Remedies for Back Pain)
Hypertension

N-Zal Related Warnings

Is the use of N-Zal safe for pregnant women?

N-Zal can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

Severe
Is the use of N-Zal safe during breastfeeding?

Women who are breastfeeding, may experience serious side effects after taking N-Zal. So it is adviced to consult the doctor before using it.

Severe
What is the effect of N-Zal on the Kidneys?

In the absence of any scientific study on the side effects of N-Zal on kidney, information on safety of N-Zal for kidney is unavailable.

Unknown
What is the effect of N-Zal on the Liver?

You may experience side effects on your liver after taking N-Zal. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

Moderate
What is the effect of N-Zal on the Heart?

N-Zal can cause side effects that could harm the heart. So medical advice before taking it is necessary.

Severe

Severe Interaction of N-Zal with Other Drugs

N-Zal should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate

Gemfibrozil

Itraconazole

N-Zal Contraindications

If you are suffering from any of the following diseases, you should not take N-Zal unless your doctor advises you to do so -

Seizures
High Blood Pressure

Frequently asked Questions about N-Zal

Is this N-Zal habit forming or addictive?

N-Zal does not cause addiction.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should not drive or operate heavy machinery after taking N-Zal as you may feel sleepy.

Dangerous
Is it safe?

N-Zal is safe but it is important to consult a doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, the use of N-Zal in mental disorders is not effective.

No

N-Zal Interactions with Food and Alcohol

Interaction between Food and N-Zal

You can take N-Zal with food.

Safe
Interaction between Alcohol and N-Zal

Consult your doctor before consuming alcohol while taking N-Zal as it can have severe side effects.

Severe