Busulfan Benefits & Uses

Busulfan is used to treat the following -

Other Benefits

Blood Cancer

Busulfan Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Chronic Myelogenous Leukemia (CML) Before or After Meal: As advised by a physician Single Maximum Dose: 0.8 mg/kg Dosage Route: Parenteral Frequency: 6 hourly Course Duration: 4 days Special Instructions: As prescribed by the doctor
Geriatric	Disease: Chronic Myelogenous Leukemia (CML) Before or After Meal: As advised by a physician Single Maximum Dose: 0.8 mg/kg Dosage Route: Parenteral Frequency: 6 hourly Course Duration: 4 days Special Instructions: As prescribed by the doctor

Busulfan Side Effects

Based on research, the following side effects have been observed when Busulfan is used -

Moderate

Edema
Chest Pain
Depression
Anemia (Read More - Home Remedies for Anaemia)
Decreased white blood cell count (neutrophils)

Mild

Nausea or vomiting
Dizziness
Dyspepsia
Rhinitis
Dry Mouth
Chills
Rash
Anxiety (Read More - Home Remedies for Anxiety)

Busulfan Related Warnings

Is the use of Busulfan safe for pregnant women?

Busulfan has many dangerous side effects in pregnant women. If you are pregnant, do not consume Busulfan without medical advice.

Severe
Is the use of Busulfan safe during breastfeeding?

Busulfan should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

Severe
What is the effect of Busulfan on the Kidneys?

Using Busulfan does not have any harmful effects on kidneys.

Safe
What is the effect of Busulfan on the Liver?

Very few cases of side effects of Busulfan on the liver have been reported.

Mild
What is the effect of Busulfan on the Heart?

Side effects of Busulfan rarely affect the heart.

Mild

Severe Interaction of Busulfan with Other Drugs

Busulfan should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Clozapine

Etanercept

Metronidazole

Nalidixic Acid

Moderate

Paracetamol

Aspirin(ASA),Paracetamol,Caffeine

Busulfan Contraindications

If you are suffering from any of the following diseases, you should not take Busulfan unless your doctor advises you to do so -

Bleeding
Blood Cancer
Neutropenia
Liver Disease

Frequently asked Questions about Busulfan

Is this Busulfan habit forming or addictive?

No, there is no any evidence that Busulfan is addictive.

No
Is it safe to drive or operate heavy machinery when consuming?

After taking Busulfan you may feel sleepy. So it is not advised to perform these activities.

Dangerous
Is it safe?

Yes, but take Busulfan only as per medical advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, Busulfan is not used to treat mental disorders.

No

Busulfan Interactions with Food and Alcohol

Interaction between Food and Busulfan

Taking Busulfan with food does not cause any problems.

Safe
Interaction between Alcohol and Busulfan

Due to lack of research, there is no information about the side effects of taking Busulfan with alcohol.

Unknown

See all substitutes for Busulfan

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 258-260

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 861

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Busulfex (busulfan)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Myleran® (busulfan)

Busulfan Injection