Dr. Ram Saini MD, MBBS , General Physician

Bigomet M can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime. 

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Bigomet M treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Bigomet M induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Dr. Sameer Awadhiya MBBS , Pediatrics

Bigomet M helps in weight loss by reducing appetite and food intake. It also increases the insulin sensitivity in your body to work more effectively. This lead to decreased glucose production increases the use of glucose and decrease the fat deposition further helps in weight loss. However, Bigomet M is not approved for weight loss, this is an off-label use.

Dr. Vipin Khadse MBBS , General Physician

Bigomet M is not a known cause of alopecia (hair loss). However, the conditions treated by Bigomet M type 2 diabetes and PCOS, often list hair loss as a possible symptom.

Dr. Ashish Mishra MBBS , Pathology

Yes, you can take Bigomet M with gliclazide, no harmful interactions have been reported between them. However, it is not necessary that no interaction can happen between these two. But before taking such kind of combination you must consult your doctor.