Amifostine Benefits & Uses

Amifostine is used to treat the following -

Other Benefits

Dry Mouth

Amifostine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Dry Mouth Before or After Meal: As advised by a physician Single Maximum Dose: 500 mg Dosage Route: Parenteral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: Before radiation therapy
Geriatric	Disease: Dry Mouth Before or After Meal: As advised by a physician Single Maximum Dose: 500 mg Dosage Route: Parenteral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: before radiation therapy

Amifostine Side Effects

Based on research, the following side effects have been observed when Amifostine is used -

Mild

Chills
Drowsiness
Fever (Read More - Home remedies for fever)
Flushing
Fatigue
Headache

Common

Nausea or vomiting

Amifostine Related Warnings

Is the use of Amifostine safe for pregnant women?

Side effects of Amifostine during pregnancy are not known because scientific research on this topic hasn't been done.

Unknown
Is the use of Amifostine safe during breastfeeding?

Due to lack of research work on this topic, the side effects of Amifostine for breastfeeding women are not known.

Unknown
What is the effect of Amifostine on the Kidneys?

Amifostine may have mild side effects on the kidneys.

Mild
What is the effect of Amifostine on the Liver?

Amifostine is completely safe for the liver.

Safe
What is the effect of Amifostine on the Heart?

Amifostine is rarely harmful for the heart.

Mild

Severe Interaction of Amifostine with Other Drugs

Amifostine should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate

Amifostine Contraindications

If you are suffering from any of the following diseases, you should not take Amifostine unless your doctor advises you to do so -

Calcium Deficiency
Low Blood Pressure
Heart Failure
Stroke
Dehydration

Frequently asked Questions about Amifostine

Is this Amifostine habit forming or addictive?

Amifostine is not addictive in nature.

No
Is it safe to drive or operate heavy machinery when consuming?

You may feel sleepy or tired after taking Amifostine. So it is best to avoid driving.

Dangerous
Is it safe?

Amifostine should be used only after doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

There is no benefit of taking Amifostine for mental disorders.

No

Amifostine Interactions with Food and Alcohol

Interaction between Food and Amifostine

Taking Amifostine with some specific foods may delay its effect. Talk to your doctor about this.

Mild
Interaction between Alcohol and Amifostine

Taking [medicine] and alcohol at the same time may lead to mild side effects. Contact your doctor right away if you observe any side effects.

Mild

See all substitutes for Amifostine

Amfos Injection - ₹1125
Cytofos Injection - ₹1000
Ethyol Injection - ₹13088
Natfost Injection - ₹93
Amifostine Injection - ₹1400

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ethyol® (amifostine)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 876

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 133-134

Amifostine Injection