Ethyfos Information

Ethyfos Injection is a cytoprotective agent used primarily to reduce the harmful side effects of certain cancer treatments. It protects healthy tissues from the toxic effects of chemotherapy and radiation while allowing these treatments to target cancer cells effectively. Amifostine Injection is indicated for:

Protection During Chemotherapy : Used to prevent kidney damage (nephrotoxicity) in patients undergoing cisplatin-based chemotherapy for advanced cancers.

Protection During Radiation Therapy : Reduces dry mouth (xerostomia) in patients receiving radiation therapy for head and neck cancers.

Amifostine is a prodrug that is converted into its active form by the enzyme alkaline phosphatase, which is more abundant in healthy cells than in tumor cells. This selective activation allows the drug to protect normal tissues from damage caused by free radicals generated during chemotherapy or radiation therapy.

Ethyfos Benefits & Uses
Ethyfos Dosage & How to Take
Ethyfos Side Effects
Ethyfos Related Warnings
Severe Interaction of Ethyfos with Other Drugs
Ethyfos Contraindications
Frequently asked Questions about Ethyfos
Ethyfos Interactions with Food and Alcohol

Ethyfos Benefits & Uses

Ethyfos is used to treat the following -

Main Benefits

Dry Mouth

Other Benefits

Chronic Kidney Disease

Ethyfos Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Dry Mouth Before or After Meal: As advised by a physician Single Maximum Dose: 500 mg Dosage Route: Parenteral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: Before radiation therapy
Geriatric	Disease: Dry Mouth Before or After Meal: As advised by a physician Single Maximum Dose: 500 mg Dosage Route: Parenteral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: before radiation therapy

Ethyfos Side Effects

Based on research, the following side effects have been observed when Ethyfos is used -

Mild

Chills
Drowsiness
Fever (Read More - Home remedies for fever)
Flushing
Fatigue
Headache

Common

Nausea or vomiting

Ethyfos Related Warnings

Is the use of Ethyfos safe for pregnant women?

Unknown
Is the use of Ethyfos safe during breastfeeding?

Unknown
What is the effect of Ethyfos on the Kidneys?

Mild
What is the effect of Ethyfos on the Liver?

Safe
What is the effect of Ethyfos on the Heart?

Mild

Severe Interaction of Ethyfos with Other Drugs

Ethyfos should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate

Ethyfos Contraindications

If you are suffering from any of the following diseases, you should not take Ethyfos unless your doctor advises you to do so -

Calcium Deficiency
Low Blood Pressure
Heart Failure
Stroke
Dehydration

Frequently asked Questions about Ethyfos

Is this Ethyfos habit forming or addictive?

No
Is it safe to drive or operate heavy machinery when consuming?

Dangerous
Is it safe?

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No

Ethyfos Interactions with Food and Alcohol

Interaction between Food and Ethyfos

Mild
Interaction between Alcohol and Ethyfos

Mild

See all substitutes for Ethyfos

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ethyol® (amifostine)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 876

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 133-134

Ethyfos 500mg Injection