Dacarbazine Benefits & Uses

Dacarbazine is used to treat the following -

Other Benefits

Hodgkin Lymphoma

Dacarbazine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Skin Cancer (Melanoma) Before or After Meal: As advised by a physician Single Maximum Dose: 4.5 mg/kg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 10 days Special Instructions: Repeat every 4 Weeks
Geriatric	Disease: Skin Cancer (Melanoma) Before or After Meal: As advised by a physician Single Maximum Dose: 4.5 mg/kg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 10 days Special Instructions: Repeat every 4 Weeks
13 - 18 years (Adolescent)	Disease: Hodgkin Lymphoma Before or After Meal: As advised by a physician Single Maximum Dose: 250 mg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 5 days Special Instructions: Repeat every 4 Weeks
2 - 12 years (Child)	Disease: Hodgkin Lymphoma Before or After Meal: As advised by a physician Single Maximum Dose: 250 mg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 5 days Special Instructions: Repeat every 4 Weeks

Dacarbazine Side Effects

Based on research, the following side effects have been observed when Dacarbazine is used -

Moderate

Erythema
Increased Liver Enzymes

Mild

Nausea or vomiting
Loss of appetite
Urticaria
Fever (Read More - Home remedies for fever)
Diarrhoea

Dacarbazine Related Warnings

Is the use of Dacarbazine safe for pregnant women?

Dacarbazine has many dangerous side effects in pregnant women. If you are pregnant, do not consume Dacarbazine without medical advice.

Severe
Is the use of Dacarbazine safe during breastfeeding?

Dacarbazine can cause moderate side effects on breastfeeding women. If you feel its side effects, then stop taking this drug and consult your doctor. Take this medicine again only if your doctor advises to do so.

Moderate
What is the effect of Dacarbazine on the Kidneys?

Dacarbazine may have mild side effects on the kidneys.

Mild
What is the effect of Dacarbazine on the Liver?

Very few cases of side effects of Dacarbazine on the liver have been reported.

Mild
What is the effect of Dacarbazine on the Heart?

Dacarbazine is rarely harmful for the heart.

Mild

Severe Interaction of Dacarbazine with Other Drugs

Dacarbazine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Clozapine

Celecoxib

Diclofenac

Ibuprofen

Dacarbazine Contraindications

If you are suffering from any of the following diseases, you should not take Dacarbazine unless your doctor advises you to do so -

Liver Disease
Kidney Disease
Neutropenia
Allergy

Frequently asked Questions about Dacarbazine

Is this Dacarbazine habit forming or addictive?

No, you will not get addicted to Dacarbazine.

No
Is it safe to drive or operate heavy machinery when consuming?

After taking Dacarbazine, you should not drive or work on any heavy machine, as Dacarbazine can make you drowsy.

Dangerous
Is it safe?

Yes, but consume Dacarbazine only on doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, Dacarbazine is not used to treat mental disorders.

No

Dacarbazine Interactions with Food and Alcohol

Interaction between Food and Dacarbazine

You can take Dacarbazine with food.

Safe
Interaction between Alcohol and Dacarbazine

Information about the interaction of Dacarbazine and alcohol is not currently available because this topic has not been researched yet.

Unknown

See all substitutes for Dacarbazine

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 388-389

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 861

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Dbl™ dacarbazine (dacarbazine)

Dacarbazine Injection