Asparaginase Benefits & Uses

Asparaginase is used to treat the following -

Other Benefits

Blood Cancer

Asparaginase Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
13 - 18 years (Adolescent)	Disease: Blood Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 200 units/kg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 4 weeks Special Instructions: As prescribed by the doctor
2 - 12 years (Child)	Disease: Blood Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 200 units/kg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 4 weeks Special Instructions: As prescribed by the doctor

Asparaginase Side Effects

Based on research, the following side effects have been observed when Asparaginase is used -

Common

Rash
Nausea or vomiting
Increased Liver Enzymes
Edema
Diarrhoea
Urticaria
Increased Glucose level in the blood
Pancreatic inflammation
Weakness
Low energy
Confusion
Dizziness

Asparaginase Related Warnings

Is the use of Asparaginase safe for pregnant women?

Asparaginase can have harmful effects in pregnant women. If you experience any discomfort after using Asparaginase, then discontinue the use and take your doctor's advice.

Moderate
Is the use of Asparaginase safe during breastfeeding?

Women who are breastfeeding may experience severe harmful effects after taking Asparaginase. It should only be taken after medical advice.

Severe
What is the effect of Asparaginase on the Kidneys?

Asparaginase has very mild side effects on the kidneys.

Mild
What is the effect of Asparaginase on the Liver?

The liver can be affected by Asparaginase. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Asparaginase only after medical advice.

Moderate
What is the effect of Asparaginase on the Heart?

You can take Asparaginase without any fear of damage to the heart.

Safe

Severe Interaction of Asparaginase with Other Drugs

Asparaginase should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Thalidomide

Moderate

Acarbose

Alogliptin

Alogliptin Tablet

Metformin

Methotrexate

Carbamazepine

Asparaginase Contraindications

If you are suffering from any of the following diseases, you should not take Asparaginase unless your doctor advises you to do so -

Liver Disease
Bleeding
Pancreatitis
Diabetes

Frequently asked Questions about Asparaginase

Is this Asparaginase habit forming or addictive?

Asparaginase does not cause addiction.

No
Is it safe to drive or operate heavy machinery when consuming?

After taking Asparaginase you may feel sleepy. So it is not advised to perform these activities.

Dangerous
Is it safe?

Asparaginase is safe but it is important to consult a doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

There is no benefit of taking Asparaginase for mental disorders.

No

Asparaginase Interactions with Food and Alcohol

Interaction between Food and Asparaginase

Taking Asparaginase with food is safe.

Safe
Interaction between Alcohol and Asparaginase

Due to lack of research, there is no information about the side effects of taking Asparaginase with alcohol.

Unknown

See all substitutes for Asparaginase

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Elspar® (Asparaginase)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 868-869

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 190-191

Asparaginase Injection