Z Texel Information

Z Texel contains Cabazitaxel, an anti-cancer medication belonging to the taxane class. It is primarily used in combination with prednisone or prednisolone to treat metastatic castration-resistant prostate cancer (mCRPC) that has progressed despite prior chemotherapy, including treatments with docetaxel. Z Texel(Cabazitaxel) is a vital therapeutic option for patients with advanced prostate cancer resistant to prior treatments. Its efficacy in extending survival must be balanced with its side effect profile, necessitating careful patient selection, premedication, and monitoring to optimize outcomes.

Indications- Metastatic Castration-Resistant Prostate Cancer (mCRPC): In combination with prednisone or prednisolone, it is used for patients whose disease has progressed after docetaxel-based therapy.

Cabazitaxel disrupts the microtubular network essential for mitotic and interphase cellular functions. By binding to tubulin, it promotes the assembly of microtubules while inhibiting their disassembly, leading to the inhibition of cell division and cancer cell proliferation.

Z Texel Benefits & Uses
Z Texel Dosage & How to Take
Z Texel Related Warnings
Severe Interaction of Z Texel with Other Drugs
Z Texel Contraindications
Frequently asked Questions about Z Texel
Z Texel Interactions with Food and Alcohol

Z Texel Benefits & Uses

Z Texel is used to treat the following -

Main Benefits

Prostate Cancer

Z Texel Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult(Male)	Disease: Prostate Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 40 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor
Geriatric	Disease: Prostate Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 40 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor

Z Texel Related Warnings

Is the use of Z Texel safe for pregnant women?

Z Texel shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

Severe
Is the use of Z Texel safe during breastfeeding?

Women who are breastfeeding may experience severe harmful effects after taking Z Texel. It should only be taken after medical advice.

Severe
What is the effect of Z Texel on the Kidneys?

Kidney can be affected by Z Texel. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.

Moderate
What is the effect of Z Texel on the Liver?

Z Texel may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

Moderate
What is the effect of Z Texel on the Heart?

Side effects of Z Texel rarely affect the heart.

Mild

Severe Interaction of Z Texel with Other Drugs

Z Texel should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Clarithromycin

Atazanavir

Chloramphenicol

Delavirdine

Delavirdine Tablet

Z Texel Contraindications

If you are suffering from any of the following diseases, you should not take Z Texel unless your doctor advises you to do so -

Drug Allergy
Neutropenia
Anemia
Liver Disease
Dehydration
Blood Infection (Sepsis)

Frequently asked Questions about Z Texel

Is this Z Texel habit forming or addictive?

Forming a habit of Z Texel has not been reported.

No
Is it safe to drive or operate heavy machinery when consuming?

Z Texel will not make you feel sleepy or drowsy. So you drive or operate machinery safely.

Safe
Is it safe?

Yes, Z Texel is safe but you must consult your doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, Z Texel is not used to treat mental disorders.

No

Z Texel Interactions with Food and Alcohol

Interaction between Food and Z Texel

Information is not available on the interaction of any foods with Z Texel, due to a lack of research on this.

Unknown
Interaction between Alcohol and Z Texel

Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Z Texel.

Unknown

See all substitutes for Z Texel

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Jevtana (cabazitaxel)

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 261-263

Z Texel 60mg Injection