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Pph is a commercial drug that is prescribed in the form of Tablet. Abortion are some of its major therapeutic uses. The alternative uses of Pph have also been explained below.
Medical history of the patient along with age and gender determines the dosage of Pph. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Detailed information has been provided in the dosage section.
Besides the aforementioned side effects, there are other adverse effects of Pph as well, which are listed below. Normally, these side effects of Pph are not long lasting and go away when the treatment is finished. Please speak with your doctor if these side effects worsen or persist for a longer duration.
It is also important to note that Pph has a Severe effect for pregnant women and Moderate effect on lactating mothers. Warnings related to Pph's effects on the liver, heart and kidney, if any, have been listed below.
The section on Pph contraindications lists all such conditions.
Besides this, Pph may also have severe interaction with some medicines. Refer to the list below for further details.
Along with the above-mentioned precautions, remember that taking Pph is considered safe while driving, and is addictive.
Pph is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
Adult(Female) |
|
Is the use of Pph safe for pregnant women?
Pregnant women may get severe side effects after taking PPH. If you are pregnant, do not take PPH without a doctor's advice.
Is the use of Pph safe during breastfeeding?
Breastfeeding women may feel side effects of PPH. If you see any side effects, stop taking PPH immediately and talk to your doctor. Take PPH again, only after your doctor's advice.
What is the effect of Pph on the Kidneys?
PPH rarely harms the kidneys.
What is the effect of Pph on the Liver?
The liver can be affected by PPH. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart PPH only after medical advice.
What is the effect of Pph on the Heart?
PPH may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.
Pph should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Pph unless your doctor advises you to do so -
Is this Pph habit forming or addictive?
Forming a habit of Pph has not been reported.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can comfortably use machinery or drive after taking Pph since it will not make you feel sleepy.
Is it safe?
Yes, but take Pph only as per medical advice.
Is it able to treat mental disorders?
No, Pph cannot treat any kind of mental disorder.
Interaction between Food and Pph
There isn't any research available on the side effects of taking Pph with food.
Interaction between Alcohol and Pph
Information about the interaction of Pph and alcohol is not currently available because this topic has not been researched yet.
PPH contains misoprostol which is a prostaglandin E1 (PGE1) analogue that possesses antisecretory property that inhibits gastric acid secretion. NSAIDs (nonsteroidal anti-inflammatory drugs) inhibits the synthesis of prostaglandins which leads to diminishing bicarbonate and mucus secretion which contributes to ulceration. PPH has mucosal protective properties that protect the stomach tissues from the damage caused by the stomach acid through decreased acid secretion and mucosal protective action. It induces labour by causing relaxation of cervix uteri (which is the lower part of the uterus). In the treatment of postpartum hemorrhage PPH works by causing contractions of smooth muscle fibres of the myometrium (middle layer of the uterine wall).
Yes, PPH alone can be taken without mifepristone it has been found to give apparently good results but it is recommended to take PPH 36-48 hours after taking mifepristone. This combination helps not only preventing excessive bleeding but it also provides better results as compared to misoprostol alone.
Yes, PPH can be taken with aspirin. No harmful drug interaction has been reported between them. It is safe to take PPH along with aspirin if it does not exceed recommended doses. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
Yes, PPH can cause a headache, this occurs rarely. It is a known side effect of this drug. However, the exact cause behind this is unknown. If you experience a severe headache after taking this drug, consider taking a mild painkiller, applying balms and complete rest. Even after this if the pain does not subside then discuss with your doctor immediately.
Yes, PPH causes bleeding this occurs due to the expelling the tissues of the fetus from the uterus. But if you observe that the heavy bleeding is continuing for more than 2 hours or usage of a sanitary napkin is more than 2 pads every hour, then this situation warrants immediate hospitalization to recover from blood loss. In case of incomplete or unsuccessful abortion, you may require surgical procedures. The heavy bleeding can be due to uterine rupture. However, this is a rare situation which occurs only in very few cases.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 867
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 654
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Cytotec® (misoprostol)