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Misoprostol is an allopathic medicine Secondary and off-label uses of Misoprostol have also been mentioned below. The correct dosage of Misoprostol depends on the patient's age, gender, and medical history. This information has been provided in detail in the dosage section.
Misoprostol is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
Adult(Female) |
|
Is the use of Misoprostol safe for pregnant women?
Misoprostol shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.
Is the use of Misoprostol safe during breastfeeding?
Misoprostol may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Misoprostol, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Misoprostol.
What is the effect of Misoprostol on the Kidneys?
Misoprostol rarely harms the kidneys.
What is the effect of Misoprostol on the Liver?
The liver can be affected by Misoprostol. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Misoprostol only after medical advice.
What is the effect of Misoprostol on the Heart?
You may experience side effects on your heart after taking Misoprostol. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.
Misoprostol should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Misoprostol unless your doctor advises you to do so -
Is this Misoprostol habit forming or addictive?
Forming a habit of Misoprostol has not been reported.
Is it safe to drive or operate heavy machinery when consuming?
Misoprostol does not cause dizziness or sleep, so you can drive a vehicle or operate machinery also.
Is it safe?
Yes, but take Misoprostol only as per medical advice.
Is it able to treat mental disorders?
No, Misoprostol cannot treat any kind of mental disorder.
Interaction between Food and Misoprostol
Information is not available on the interaction of any foods with Misoprostol, due to a lack of research on this.
Interaction between Alcohol and Misoprostol
No research has been done on this till date. Therefore, it is not known what the effect of taking Misoprostol with alcohol will be.
The dosage of Misoprostol may vary from case to case and type of condition in which the drug is being given. You are advised to take Misoprostol as prescribed by your doctor. Ideally, it should be taken with the food to minimize the possibility of stomach irritation that can result in diarrhoea. Precautions must be taken in patients with known inflammatory bowel disease, improper kidney function, coronary artery disease, and hypertension.
Yes, Misoprostol causes abdominal (stomach) pain but it occurs in only a few cases. It is a known side effect of this drug. If you experience abdominal (stomach) pain after taking this drug, consider taking a mild painkiller. Even if the pain does not subside or becomes more severe then in any circumstances do not self-medicate yourself further contact your doctor right away.
Misoprostol contains misoprostol which is a prostaglandin E1 (PGE1) analogue that possesses antisecretory property that inhibits gastric acid secretion. NSAIDs (nonsteroidal anti-inflammatory drugs) inhibits the synthesis of prostaglandins which leads to diminishing bicarbonate and mucus secretion which contributes to ulceration. Misoprostol has mucosal protective properties that protect the stomach tissues from the damage caused by the stomach acid through decreased acid secretion and mucosal protective action. It induces labour by causing relaxation of cervix uteri (which is the lower part of the uterus). In the treatment of postpartum hemorrhage Misoprostol works by causing contractions of smooth muscle fibres of the myometrium (middle layer of the uterine wall).
Yes, Misoprostol can be taken with ibuprofen. No harmful drug interaction has been reported between them. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
No, Misoprostol should not be discontinued without doctors advice. You are recommended to always consult a doctor before discontinuing this medicine.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 867
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 654
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Cytotec® (misoprostol)