Onset (Zota): Uses, Price, Dosage, Side Effects, Substitute, Buy Online

Onset (Zota) Benefits & Uses

Onset (Zota) is used to treat the following -

Main Benefits

Nausea and Vomiting (Read More - Home remedies for nausea and vomiting)

Onset (Zota) Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Nausea and Vomiting Before or After Meal: As advised by a physician Single Maximum Dose: 0.15 mg/kg Dosage Route: Parenteral Frequency: once only Course Duration: As directed by the doctor Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Geriatric	Disease: Nausea and Vomiting Before or After Meal: As advised by a physician Single Maximum Dose: 0.15 mg/kg Dosage Route: Parenteral Frequency: once only Course Duration: As directed by the doctor Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
13 - 18 years (Adolescent)	Disease: Nausea and Vomiting Before or After Meal: As advised by a physician Single Maximum Dose: 0.15 mg/kg Dosage Route: Parenteral Frequency: once only Course Duration: As directed by the doctor Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
2 - 12 years (Child)	Disease: Nausea and Vomiting Before or After Meal: As advised by a physician Single Maximum Dose: 0.15 mg/kg Dosage Route: Parenteral Frequency: once only Course Duration: As directed by the doctor Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Infant (1 month to 2 years)	Disease: Nausea and Vomiting Before or After Meal: As advised by a physician Single Maximum Dose: 0.15 mg/kg Dosage Route: Parenteral Frequency: once only Course Duration: As directed by the doctor Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy. Given dose older then 6 month

Onset (Zota) Side Effects

Based on research, the following side effects have been observed when Onset (Zota) is used -

Moderate

Constipation (Read More - Home remedies for constipation)
Urine Retention

Mild

Fatigue
Headache
Dizziness (Read More - Home Remedies for Dizziness: Quick Tips for Instant Relief)
Fever (Read More - Home remedies for fever)
Anxiety (Read More - Home Remedies for Anxiety)
Chills
Agitation
Drowsiness
Diarrhoea
Injection Site Allergic Reaction
Rash
Paresthesia

Onset (Zota) Related Warnings

Is the use of Onset (Zota) safe for pregnant women?

Onset (Zota) is safe to take during pregnancy.

Safe
Is the use of Onset (Zota) safe during breastfeeding?

Side effects of Onset (Zota) for breastfeeding are little to none, so you can take it without doctor's advice.

Mild
What is the effect of Onset (Zota) on the Kidneys?

Using Onset (Zota) does not have any harmful effects on kidneys.

Safe
What is the effect of Onset (Zota) on the Liver?

There may be an adverse effect on the liver after taking Onset (Zota). If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

Moderate
What is the effect of Onset (Zota) on the Heart?

You may experience side effects on your heart after taking Onset (Zota). If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.

Moderate

Severe Interaction of Onset (Zota) with Other Drugs

Onset (Zota) should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Amiodarone

Tramadol

Sotalol

Paracetamol,Chlorpheniramine,Dextromethorphan

Moderate

Aripiprazole

Asenapine

Onset (Zota) Contraindications

If you are suffering from any of the following diseases, you should not take Onset (Zota) unless your doctor advises you to do so -

Heart Disease
Liver Disease
Phenylketonuria (PKU)
Calcium Deficiency
Potassium Deficiency

Frequently asked Questions about Onset (Zota)

Is this Onset (Zota) habit forming or addictive?

Onset (Zota) is not addictive in nature.

No
Is it safe to drive or operate heavy machinery when consuming?

After taking Onset (Zota), you should not drive or work on any heavy machine, as Onset (Zota) can make you drowsy.

Dangerous
Is it safe?

Onset (Zota) is safe but it is important to consult a doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, Onset (Zota) is not used to treat mental disorders.

No

Onset (Zota) Interactions with Food and Alcohol

Interaction between Food and Onset (Zota)

Taking Onset (Zota) with food does not harm your health.

Safe
Interaction between Alcohol and Onset (Zota)

Taking Onset (Zota) with alcohol can have severely harmful effects on your health.

Severe

Frequently asked Questions about Onset (Zota)

Question over 5 years ago

Why Onset (Zota) is prescribed post surgery?

Dr. Yogesh Kumar MBBS , General Physician

Yes, Onset (Zota) is usually administered before and after surgery for treating post-anesthesia shivering (PAS) and nausea. PAS is a condition in which tremors of head, neck, trunk, shoulder, and extremities. It greatly reduces the quality of life of a patient since it causes discomfort and increases pain. It disturbs surgical care and increases the stress on cardiopulmonary functions. Hence as a precautionary measure, this medicine is administered to prevent unpleasant anesthetic effects.

Question about 6 years ago

How does Onset (Zota) work?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Onset (Zota) belongs to a class of compounds known as 5 -HT3 receptor antagonists. It blocks the action of serotonin completely at the 5-HT3 receptor sites present in our brain (vomiting centre) which provides relief to the patient from nausea and vomiting.

Question over 5 years ago

Can Onset (Zota) be used for anxiety?

Dr. Piyush Malav MBBS, MS , General Surgery

Yes, Onset (Zota) can be used for the symptom alleviation in anxiety, however, more clinical trials are needed to confirm this association. Anxiety can also be effectively managed by breathing deeply, practicing meditation, and not taking much stress. In case of severe anxiety please speak to your doctor.

Question almost 6 years ago

Does Onset (Zota) cause constipation?

Dr. Ashish Mishra MBBS , Pathology

Yes, Onset (Zota) can cause constipation. Some of the other side effects are a headache and dizziness. Constipation is a debilitating disorder which can be prevented by drinking a lot of water, eating more of fiber, exercising more, taking herbal laxatives, taking probiotic food, and avoiding dairy products.

Question over 5 years ago

Does Onset (Zota) cause drowsiness?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Yes, Onset (Zota) may cause drowsiness because this drug has been reported to induce sleep. Ensure you do not drive or do some high precision work. To avoid excessive drowsiness with this medicine you are encouraged to take adequate night-time sleep, keeping distractions out of the bedroom, going to sleep and getting up at consistent times, eating light at lunchtime, putting in some form of a physical activity, avoiding taking naps during the day, and avoiding alcohol at night.