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Onset (Zota) is a commercial drug that is prescribed in the form of Injection. It is typically used for the treatment of Nausea and Vomiting.
Medical history of the patient along with age and gender determines the dosage of Onset (Zota). The condition it has been prescribed for, and the route of administration also determine the right dosage. Refer to the dosage section for a detailed discussion.
While these are the most often observed Onset (Zota) side effects, there are can be others also. These have been listed below. Such side effects of Onset (Zota) normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.
It is also important to note that Onset (Zota) has a Safe effect for pregnant women and Mild effect on lactating mothers. Further, the section on Onset (Zota) related warnings talks about Onset (Zota)'s effects on the liver, heart and kidney.
Onset (Zota) can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Onset (Zota) in conditions like Heart Disease, Calcium Deficiency, Potassium Deficiency. Other conditions have been mentioned below in the Onset (Zota) contraindications section.
Additionally, Onset (Zota) may also adversely react with other medicines. A complete list of these interactions is given below.
In addition to the above precautions for Onset (Zota), it is important to know that it is not safe while driving, and is not habit-forming.
Onset (Zota) is used to treat the following -
Main Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Infant (1 month to 2 years) |
|
Is the use of Onset (Zota) safe for pregnant women?
Onset (Zota) is safe to take during pregnancy.
Is the use of Onset (Zota) safe during breastfeeding?
Side effects of Onset (Zota) for breastfeeding are little to none, so you can take it without doctor's advice.
What is the effect of Onset (Zota) on the Kidneys?
Using Onset (Zota) does not have any harmful effects on kidneys.
What is the effect of Onset (Zota) on the Liver?
There may be an adverse effect on the liver after taking Onset (Zota). If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.
What is the effect of Onset (Zota) on the Heart?
You may experience side effects on your heart after taking Onset (Zota). If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.
Onset (Zota) should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Onset (Zota) unless your doctor advises you to do so -
Is this Onset (Zota) habit forming or addictive?
Onset (Zota) is not addictive in nature.
Is it safe to drive or operate heavy machinery when consuming?
After taking Onset (Zota), you should not drive or work on any heavy machine, as Onset (Zota) can make you drowsy.
Is it safe?
Onset (Zota) is safe but it is important to consult a doctor before taking it.
Is it able to treat mental disorders?
No, Onset (Zota) is not used to treat mental disorders.
Interaction between Food and Onset (Zota)
Taking Onset (Zota) with food does not harm your health.
Interaction between Alcohol and Onset (Zota)
Taking Onset (Zota) with alcohol can have severely harmful effects on your health.
It is not recommended that you discontinue taking Onset (Zota) on your own. Discontinuing Onset (Zota) may lead to unwanted side effects of chemotherapy and radiation therapy such as excessive vomiting. You must speak to your doctor first as this will help you to take an informed decision.
Yes, Onset (Zota) can be taken for the treatment of irritable bowel syndrome with diarrhea. Irritable bowel syndrome is a common gastrointestinal disorder affecting a lot of people. It causes gas, abdominal discomfort and changes in the bowel movement like diarrhea or constipation. The disease can be controlled by altering the diet and eating more of fibre and less of fats, alcohol, caffeine and spicy food. Increasing physical activity and reducing stress can also help greatly.
Yes, it is safe to take Onset (Zota) for as long as it is prescribed by your doctor. Do not take more or less of Onset (Zota), more frequently or less frequently. It is important to follow the recommendations of your doctor completely.
Onset (Zota) is a brand name for ondansetron. It belongs to a class of compounds known as serotonin type 3 receptor antagonists. It is available in the form of tablet and injection. It is used to prevent nausea and vomiting that is caused by anti-cancer drugs, chemotherapy and radiation therapy. It is also used to prevent post-surgical nausea and vomiting.
Yes, Onset (Zota) can cause constipation. Some of the other side effects are a headache and dizziness. Constipation is a debilitating disorder which can be prevented by drinking a lot of water, eating more of fiber, exercising more, taking herbal laxatives, taking probiotic food, and avoiding dairy products.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)