Lindoshil 25mg Capsule

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10 Capsule in 1 Strip Out of Stock
₹ 3040
10 Capsule 1 Strip ₹ 3040
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Lindoshil 25mg Capsule

10 Capsule in 1 Strip
₹ 3040
10 Capsule | 1 Strip
₹ 3040
0 people have bought this recently

Lindoshil 25mg Capsule Information

Lindoshil, containing the active ingredient Lenalidomide, is a medication primarily used in the treatment of multiple myeloma and myelodysplastic syndromes. It belongs to a class of drugs known as immunomodulatory agents, which enhance the immune system's response to target cancer cells.

Indications

  • Multiple Myeloma (in combination with dexamethasone)

  • Myelodysplastic Syndromes (MDS) with deletion 5q cytogenetic abnormality

  • Mantle Cell Lymphoma (after at least one prior therapy)

Mechanism of Action

Lenalidomide works by modulating the immune system, inhibiting angiogenesis (the growth of new blood vessels that tumors need to grow), and promoting the destruction of cancer cells. It affects cytokine production and enhances T-cell and natural killer cell activity.

Dosage and Administration

  • Multiple Myeloma: 25 mg once daily on days 1 to 21 of repeated 28-day cycles.

  • Myelodysplastic Syndromes: 10 mg once daily.

  • Mantle Cell Lymphoma: 25 mg once daily on days 1 to 21 of each 28-day cycle.

Note: Doses may be adjusted based on patient tolerance and medical condition.

Onset and Duration of Action

  • Onset of Action: Variable; improvement in blood counts may be seen within 4 weeks for MDS.

  • Duration of Action: Depends on the indication and patient response.

Side Effects

Common side effects include:

  • Fatigue

  • Diarrhea

  • Nausea

  • Rash

  • Neutropenia

  • Thrombocytopenia

Serious side effects:

  • Blood clots

  • Tumor lysis syndrome

  • Hepatotoxicity

  • Hypersensitivity reactions

Precautions

  • Pregnancy: Contraindicated due to severe risk of birth defects.

  • Hematologic Monitoring: Regular blood tests are required to monitor for cytopenias.

  • Infections: Risk of serious infections; prophylactic measures may be needed.

  • Renal Impairment: Dose adjustment is required.

Contraindications

  • Pregnancy

  • Severe hypersensitivity to Lenalidomide or its components

Drug Interactions

  • Increased risk of thrombosis when used with corticosteroids or erythropoietic agents.

  • Interaction with warfarin may increase bleeding risk.

Storage

Store at room temperature (15°C to 30°C) away from moisture and direct light.



Lindoshil 25mg Capsule Benefits & Uses

Lindoshil 25mg Capsule is used to treat the following -

Main Benefits

Other Benefits

Lindoshil 25mg Capsule Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Multiple Myeloma
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 3 weeks
  • Special Instructions: Repeat cycle in every 28 days
Geriatric
  • Disease: Multiple Myeloma
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 3 weeks
  • Special Instructions: Repeat cycle in every 28 days


Lindoshil 25mg Capsule Side Effects

Based on research, the following side effects have been observed when Lindoshil 25mg Capsule is used -

Mild

Common

Lindoshil 25mg Capsule Related Warnings

  • Is the use of Lindoshil 25mg Capsule safe for pregnant women?


    Lindoshil has many dangerous side effects in pregnant women. If you are pregnant, do not consume Lindoshil without medical advice.

    Severe
  • Is the use of Lindoshil 25mg Capsule safe during breastfeeding?


    Lindoshil may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

    Severe
  • What is the effect of Lindoshil 25mg Capsule on the Kidneys?


    There may be some adverse effects on kidney after taking Lindoshil. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Lindoshil 25mg Capsule on the Liver?


    There may be an adverse effect on the liver after taking Lindoshil. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Lindoshil 25mg Capsule on the Heart?


    You may experience side effects on your heart after taking Lindoshil. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.

    Moderate


Severe Interaction of Lindoshil 25mg Capsule with Other Drugs

Lindoshil 25mg Capsule should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Lindoshil 25mg Capsule Contraindications

If you are suffering from any of the following diseases, you should not take Lindoshil 25mg Capsule unless your doctor advises you to do so -



Frequently asked Questions about Lindoshil 25mg Capsule

  • Is this Lindoshil 25mg Capsule habit forming or addictive?


    Forming a habit of Lindoshil 25mg Capsule has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Lindoshil 25mg Capsule, you should not drive or work on any heavy machine, as Lindoshil 25mg Capsule can make you drowsy.

    Dangerous
  • Is it safe?


    Yes, Lindoshil 25mg Capsule is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Lindoshil 25mg Capsule for mental disorders.

    No

Lindoshil 25mg Capsule Interactions with Food and Alcohol

  • Interaction between Food and Lindoshil 25mg Capsule


    Taking Lindoshil 25mg Capsule with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Lindoshil 25mg Capsule


    Due to lack of research, there is no information about the side effects of taking Lindoshil 25mg Capsule with alcohol.

    Unknown


See all substitutes for Lindoshil



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 753-755

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Revlimid (lenalidomide)



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₹3040
10 Capsule in 1 Strip