Kabimustine

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₹ 2516.06
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Kabimustine Information

Kabimustine is a chemotherapy medication used in the treatment of certain cancers, including chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma (NHL). It belongs to the class of drugs known as alkylating agents and is available as an injection for intravenous use. Kabimustine works by damaging the DNA of cancer cells, which prevents them from dividing and leads to their destruction. This dual-action mechanism-alkylation and disruption of DNA repair pathways-makes it effective in targeting rapidly growing cancer cells.

Indications:

  • Chronic Lymphocytic Leukemia (CLL)
  • Indolent Non-Hodgkin's Lymphoma (iNHL) that has not responded to other treatments
  • Off-label uses as determined by oncologists

 


Kabimustine Benefits & Uses

Kabimustine is used to treat the following -

Other Benefits

Kabimustine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Chronic Lymphocytic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 160 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 2 days
  • Special Instructions: Take on days 1 and 2 of a 28-day cycle Up to 6 cycles
Geriatric
  • Disease: Chronic Lymphocytic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 160 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 2 days
  • Special Instructions: Take on days 1 and 2 of a 28-day cycle Up to 6 cycle

Kabimustine Side Effects

Based on research, the following side effects have been observed when Kabimustine is used -

Severe

Moderate

Mild

Kabimustine Related Warnings

  • Is the use of Kabimustine safe for pregnant women?


    Kabimustine can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Kabimustine safe during breastfeeding?


    Kabimustine should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Kabimustine on the Kidneys?


    Kabimustine can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Kabimustine on the Liver?


    Very few cases of side effects of Kabimustine on the liver have been reported.

    Mild
  • What is the effect of Kabimustine on the Heart?


    The heart can be affected by Kabimustine. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

    Moderate

Severe Interaction of Kabimustine with Other Drugs

Kabimustine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Kabimustine Contraindications

If you are suffering from any of the following diseases, you should not take Kabimustine unless your doctor advises you to do so -


Frequently asked Questions about Kabimustine

  • Is this Kabimustine habit forming or addictive?


    Forming a habit of Kabimustine has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Kabimustine since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Kabimustine is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Kabimustine cannot treat any kind of mental disorder.

    No

Kabimustine Interactions with Food and Alcohol

  • Interaction between Food and Kabimustine


    There isn't any research available on the side effects of taking Kabimustine with food.

    Unknown
  • Interaction between Alcohol and Kabimustine


    Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Kabimustine.

    Unknown

See all substitutes for Kabimustine


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 16

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Treanda® (bendamustine hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Bendeka™(bendamustine hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Belrapzo™ (bendamustine hydrochloride injection)


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₹2516
1 Injection in 1 Vial