Genmus

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Genmus Information

Genmus is a chemotherapy medication used in the treatment of certain cancers, including chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma (NHL). It belongs to the class of drugs known as alkylating agents and is available as an injection for intravenous use. Genmus works by damaging the DNA of cancer cells, which prevents them from dividing and leads to their destruction. This dual-action mechanism-alkylation and disruption of DNA repair pathways-makes it effective in targeting rapidly growing cancer cells.

Indications:

  • Chronic Lymphocytic Leukemia (CLL)
  • Indolent Non-Hodgkin's Lymphoma (iNHL) that has not responded to other treatments
  • Off-label uses as determined by oncologists

Genmus Benefits & Uses

Genmus is used to treat the following -

Other Benefits

Genmus Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Chronic Lymphocytic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 160 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 2 days
  • Special Instructions: Take on days 1 and 2 of a 28-day cycle Up to 6 cycles
Geriatric
  • Disease: Chronic Lymphocytic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 160 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: 2 days
  • Special Instructions: Take on days 1 and 2 of a 28-day cycle Up to 6 cycle

Genmus Side Effects

Based on research, the following side effects have been observed when Genmus is used -

Severe

Moderate

Mild

Genmus Related Warnings

  • Is the use of Genmus safe for pregnant women?


    Genmus has many dangerous side effects in pregnant women. If you are pregnant, do not consume Genmus without medical advice.

    Severe
  • Is the use of Genmus safe during breastfeeding?


    Genmus should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Genmus on the Kidneys?


    There may be some adverse effects on kidney after taking Genmus. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Genmus on the Liver?


    Very few cases of side effects of Genmus on the liver have been reported.

    Mild
  • What is the effect of Genmus on the Heart?


    Genmus may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate

Severe Interaction of Genmus with Other Drugs

Genmus should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Genmus Contraindications

If you are suffering from any of the following diseases, you should not take Genmus unless your doctor advises you to do so -


Frequently asked Questions about Genmus

  • Is this Genmus habit forming or addictive?


    No, you will not get addicted to Genmus.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can operate a vehicle or heavy machinery after taking Genmus since it does not cause drowsiness.

    Safe
  • Is it safe?


    Genmus is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Genmus is unable to treat or cure mental disorders.

    No

Genmus Interactions with Food and Alcohol

  • Interaction between Food and Genmus


    Due to a lack of research, nothing can be said about the consequences of taking Genmus together with food.

    Unknown
  • Interaction between Alcohol and Genmus


    Due to lack of research, there is no information about the side effects of taking Genmus with alcohol.

    Unknown

See all substitutes for Genmus


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 16

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Treanda® (bendamustine hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Bendeka™(bendamustine hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Belrapzo™ (bendamustine hydrochloride injection)


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