Advamab

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Select the variant of Advamab

Advamab 100mg Injection 4ml इंजेक्शन 1 शीशी ₹ 12900
Advamab 400mg Injection 16ml इंजेक्शन 1 शीशी ₹ 45870

Advamab Information

Advamab is a monoclonal antibody used in the treatment of various cancers. It works by inhibiting angiogenesis, the process by which tumors develop new blood vessels to sustain their growth. Advamab specifically binds to vascular endothelial growth factor (VEGF), a protein that promotes the formation of new blood vessels. By neutralizing VEGF, Advamab starves tumors of their blood supply, inhibiting growth and progression. 

Indications:

  • Colorectal Cancer: Advanced or metastatic stages, often in combination with chemotherapy.
  • Non-Small Cell Lung Cancer (NSCLC): Metastatic cases, in combination with chemotherapy.
  • Renal Cell Carcinoma (RCC): Advanced stages, often combined with interferon alfa.
  • Cervical Cancer: Persistent, recurrent, or metastatic cases.
  • Glioblastoma: As a second-line treatment.
  • Ovarian Cancer: Platinum-resistant and recurrent forms.

Advamab is a cornerstone in targeted cancer therapy due to its innovative approach to halting tumor growth. However, its use requires careful consideration of patient-specific factors and potential side effects. Collaborating with oncologists and monitoring during treatment ensures the best outcomes for patients.


Advamab Benefits & Uses

Advamab is used to treat the following -

Main Benefits

Other Benefits

Advamab Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Kidney Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Ovarian Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Kidney Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 2 Weekly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Advamab Side Effects

Based on research, the following side effects have been observed when Advamab is used -

Severe

Moderate

Mild

Common

Unknown

Advamab Related Warnings

  • Is the use of Advamab safe for pregnant women?


    Advamab shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Advamab safe during breastfeeding?


    Women who are breastfeeding, may experience serious side effects after taking Advamab. So it is adviced to consult the doctor before using it.

    Severe
  • What is the effect of Advamab on the Kidneys?


    There can be some harmful effects on your kidneys after taking Advamab. If you witness any side effects, discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Advamab on the Liver?


    Advamab can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Advamab on the Heart?


    You may experience side effects on your heart after taking Advamab. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.

    Moderate

Severe Interaction of Advamab with Other Drugs

Advamab should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Advamab Contraindications

If you are suffering from any of the following diseases, you should not take Advamab unless your doctor advises you to do so -


Frequently asked Questions about Advamab

  • Is this Advamab habit forming or addictive?


    Forming a habit of Advamab has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Advamab you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Advamab should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Advamab for mental disorders.

    No

Advamab Interactions with Food and Alcohol

  • Interaction between Food and Advamab


    Taking Advamab with food is safe.

    Safe
  • Interaction between Alcohol and Advamab


    No research has been done on this till date. Therefore, it is not known what the effect of taking Advamab with alcohol will be.

    Unknown

See all substitutes for Advamab


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 224-225

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 871

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Avastin® (bevacizumab)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Avastin® (bevacizumab)


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