Zofer

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    Zofer Information

    Zofer is a prescription medicine that is available as a Syrup,Tablet,Injection. Nausea and Vomiting are some of its major therapeutic uses.

    The optimal dosage of Zofer is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. Detailed information has been provided in the dosage section.

    Some other side effects of Zofer have been listed ahead. Such side effects of Zofer normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

    In addition, Zofer's effect is Safe during pregnancy and Mild for lactating mothers. In addition, Zofer's effects on the liver, heart and kidney are discussed below in the Zofer related warnings section.

    Zofer can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Zofer in conditions like Heart Disease, Calcium Deficiency, Potassium Deficiency. Other conditions have been mentioned below in the Zofer contraindications section.

    Additionally, Zofer may also adversely react with other medicines. See below for a complete list.

    You should also be aware that Zofer is not safe while driving, and is not addiction.


    Zofer Benefits & Uses

    Zofer is used to treat the following -

    Zofer Dosage & How to Take

    This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

    Find the right dosage based on disease and age

    Age Group Dosage
    Adult
    • Disease: Nausea and Vomiting
    • Before or After Meal: Either
    • Single Maximum Dose: 8 mg
    • Dosage Form: Tablet
    • Dosage Route: Oral
    • Frequency: 2 daily
    • Course Duration: 2 days
    • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
    Geriatric
    • Disease: Nausea and Vomiting
    • Before or After Meal: Either
    • Single Maximum Dose: 8 mg
    • Dosage Form: Tablet
    • Dosage Route: Oral
    • Frequency: 2 daily
    • Course Duration: 2 days
    • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
    13 - 18 years (Adolescent)
    • Disease: Nausea and Vomiting
    • Before or After Meal: Either
    • Single Maximum Dose: 8 mg
    • Dosage Form: Tablet
    • Dosage Route: Oral
    • Frequency: 2 daily
    • Course Duration: 5 days
    • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
    2 - 12 years (Child)
    • Disease: Nausea and Vomiting
    • Before or After Meal: Either
    • Single Maximum Dose: 4 mg
    • Dosage Form: Tablet
    • Dosage Route: Oral
    • Frequency: 3 daily
    • Course Duration: 5 days
    • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy

    Zofer Side Effects

    Based on research, the following side effects have been observed when Zofer is used -

    Moderate

    Mild

    Zofer Related Warnings

    • Is the use of Zofer safe for pregnant women?


      Zofer is safe for pregnant women.

      Safe
    • Is the use of Zofer safe during breastfeeding?


      Zofer may have very limited harmful effects for breastfeeding women.

      Mild
    • What is the effect of Zofer on the Kidneys?


      Zofer does not damage the kidneys.

      Safe
    • What is the effect of Zofer on the Liver?


      The liver can be affected by Zofer. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Zofer only after medical advice.

      Moderate
    • What is the effect of Zofer on the Heart?


      Zofer can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

      Moderate

    Severe Interaction of Zofer with Other Drugs

    Zofer should not be taken with following medicines due to severe side effects it may cause to patients -

    Severe

    Moderate


    Zofer Contraindications

    If you are suffering from any of the following diseases, you should not take Zofer unless your doctor advises you to do so -


    Frequently asked Questions about Zofer

    • Is this Zofer habit forming or addictive?


      No, there is no any evidence that Zofer is addictive.

      No
    • Is it safe to drive or operate heavy machinery when consuming?


      No, you should do not do anything that requires concentration and attention as the Zofer can make you feel drowsy.

      Dangerous
    • Is it safe?


      Yes, but consume Zofer only on doctor's advice.

      Safe, but take only on Doctor's advise
    • Is it able to treat mental disorders?


      No, Zofer is not used to treat mental disorders.

      No

    Zofer Interactions with Food and Alcohol

    • Interaction between Food and Zofer


      You can take Zofer with food.

      Safe
    • Interaction between Alcohol and Zofer


      Consuming Zofer with alcohol can have many serious effects on your body.

      Severe

    Frequently asked Questions about Zofer

    Question almost 6 years ago

    Can Zofer be taken for motion sickness?

    Dr. Ajay Kumar. MBBS, MD , Psychiatry, General Physician, Infectious Disease, Sexology, Internal Medicine, Venereology, Diabetology

    No, Zofer is not found to be effective against motion sickness. It prevents vomiting due to chemotherapeutic drugs and radiation. Motion sickness is the disturbance of the inner ear caused by a lot of motion. It can be prevented by not taking too much food or too many drinks or alcohol just before the travel. One should also avoid food with very strong odours. One should avoid reading while traveling. One should also sit in the direction of the travel. One should sit in the front. Open a vent of fresh air and try to be relaxed while traveling. 

    Question almost 6 years ago

    How long can I take Zofer?

    Dr. Ramraj Meena MBBS , General Physician

    Zofer must be taken for as long as it is prescribed by your doctor. You must not take more or less of it as it may cause side effects or disease relapse. 

    Question over 5 years ago

    Does Zofer cause headache?

    Dr. MBBS , Pediatrics, Dermatology, General Physician, Dietician, Infectious Disease, Sexual Medicine & Marital Therapy, Obstetrics & Gynaecology, AIDS/HIV Sexually Transmitted Infections

    Yes, headache is one of the common side effects of Zofer. Apply balms and take a mild painkiller if a headache is of throbbing nature. Additionally, headaches can be prevented by doing yoga and meditation, by keeping away from electronic gadgets and computers, by eating light food and listening to relaxing music.

    Question about 6 years ago

    How does Zofer work?

    Dr. Uday Nath Sahoo MBBS , Internal Medicine

    Zofer belongs to a class of compounds known as 5 -HT3 receptor antagonists. It blocks the action of serotonin completely at the 5-HT3 receptor sites present in our brain (vomiting centre) which provides relief to the patient from nausea and vomiting.

    Question about 6 years ago

    What is Zofer?

    Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

    Zofer is a brand name for ondansetron. It belongs to a class of compounds known as serotonin type 3 receptor antagonists. It is available in the form of tablet and injection. It is used to prevent nausea and vomiting that is caused by anti-cancer drugs, chemotherapy and radiation therapy. It is also used to prevent post-surgical nausea and vomiting. 


    See all substitutes for Zofer


    This medicine data has been created by -

    Vikas Chauhan

    B.Pharma, Pharmacy
    5 Years of Experience


    References

    April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948

    KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668

    US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)

    US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)


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