Dr. Kishan Barnwal MBBS , General Physician

No, Letrofil does not contain HCG (human chorionic gonadotropin) but it can stimulate the release of HCG in the body. Letrofil contains letrozole which is used for the treatment of female infertility and breast cancer. 

Dr. Suhas Bhargav MBBS , General Physician

Yes, Letrofil may cause breast pain. It is a rare side effect of this drug. However, the exact cause behind breast pain is not known. If you are experiencing excessive breast pain then discuss it with your doctor.

Dr. Vipin Khadse MBBS , General Physician

Yes, Letrofil might be used in the treatment of endometriosis along with other drugs but generally, it is not preferred as the first-line drug of choice for endometriosis.

Dr. Madhur Anand MBBS, MS , General Surgery

Letrofil contains letrozole that works in breast cancer by blocking an enzyme (aromatase) which prevents the conversion of androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) due to this levels of estrogen hormones drop in the body. The decrease in hormone levels leads to a reduction in tumor mass or delays the progression of tumor growth in some women. For an ovulation (infertility), it is presumed that Letrofil works by increasing the sensitivity of ovary to follicular stimulating hormone (FSH) and also low level of estrogen hormones in the blood is detected by the brain which in turn increases the production of a follicular stimulating hormone (FSH) which causes induction of ovulation.

Dr. Chinmaya Bal MBBS , General Physician

Yes Letrofil can be taken along with tamoxifen at the same time because tamoxifen decreases levels of letrozole by unknown mechanism. Hence taking Letrofil with tamoxifen at the same time should be avoided.