Oxaliplatin Benefits & Uses

Oxaliplatin is used to treat the following -

Other Benefits

Oxaliplatin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Colorectal Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 140 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: 6 months Special Instructions: Given 85 mg/m2 as IV infusion with combination of 5-fluorouracil/leucovorin in every 2 weeks
Geriatric	Disease: Colorectal Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 140 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: 6 months Special Instructions: Given 85 mg/m2 as IV infusion with combination of 5-fluorouracil/leucovorin in every 2 weeks

Oxaliplatin Side Effects

Based on research, the following side effects have been observed when Oxaliplatin is used -

Severe

Anemia (Read More - Home Remedies for Anaemia)
Decreased white blood cell count (neutrophils)
Peripheral Neuropathy

Moderate

Increased Liver Enzymes
Stomatitis (Inflammation of the mouth)

Mild

Nausea or vomiting
Fatigue
Diarrhoea
Rhinitis
Dyspepsia
Insomnia
Dizziness
Injection Site Allergic Reaction
पेट की गैस
Hair Loss
Loss of appetite

Oxaliplatin Related Warnings

Is the use of Oxaliplatin safe for pregnant women?

Oxaliplatin can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

Severe
Is the use of Oxaliplatin safe during breastfeeding?

Women who are breastfeeding, may experience serious side effects after taking Oxaliplatin. So it is adviced to consult the doctor before using it.

Severe
What is the effect of Oxaliplatin on the Kidneys?

Very few cases of side effects of Oxaliplatin on kidney have been reported.

Mild
What is the effect of Oxaliplatin on the Liver?

Oxaliplatin can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

Moderate
What is the effect of Oxaliplatin on the Heart?

Oxaliplatin may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

Moderate

Severe Interaction of Oxaliplatin with Other Drugs

Oxaliplatin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Amiodarone

Clozapine

Fentanyl

Etanercept

Haloperidol

Emtricitabine,Tenofovir,Efavirenz

Moderate

Aspirin

Azithromycin

Oxaliplatin Contraindications

If you are suffering from any of the following diseases, you should not take Oxaliplatin unless your doctor advises you to do so -

Heart Disease
Liver Disease
Neutropenia
Peripheral Neuropathy
Arrhythmia

Frequently asked Questions about Oxaliplatin

Is this Oxaliplatin habit forming or addictive?

Forming a habit of Oxaliplatin has not been reported.

No
Is it safe to drive or operate heavy machinery when consuming?

After taking Oxaliplatin, you should not drive or work on any heavy machine, as Oxaliplatin can make you drowsy.

Dangerous
Is it safe?

Yes, Oxaliplatin is safe but you must consult your doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, the use of Oxaliplatin in mental disorders is not effective.

No

Oxaliplatin Interactions with Food and Alcohol

Interaction between Food and Oxaliplatin

It is safe to take Oxaliplatin with food.

Safe
Interaction between Alcohol and Oxaliplatin

Consult your doctor before consuming alcohol while taking Oxaliplatin as it can have severe side effects.

Severe

See all substitutes for Oxaliplatin

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 954-956

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Eloxatin (oxaliplatin)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Oxaliplan™ (oxaliplatin)

Oxaliplatin Infusion