Primidone Benefits & Uses

Primidone is used to treat the following -

Main Benefits

Epilepsy

Primidone Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Epilepsy Before or After Meal: Either Single Maximum Dose: 250 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 3 daily Course Duration: As directed by the doctor Special Instructions: Dosage range: 750 - 2000 mg/day as needed
Geriatric	Disease: Epilepsy Before or After Meal: Either Single Maximum Dose: 250 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 3 daily Course Duration: As directed by the doctor Special Instructions: Dosage range: 750 - 2000 mg/day as needed
13 - 18 years (Adolescent)	Disease: Epilepsy Before or After Meal: Either Single Maximum Dose: 250 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 3 daily Course Duration: As directed by the doctor Special Instructions: Dosage range: 750 - 2000 mg/day as needed
2 - 12 years (Child)	Disease: Epilepsy Before or After Meal: Either Single Maximum Dose: 25 mg/kg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: dose may increase 1000 mg/day as needed, children age less than 8 years
Infant (1 month to 2 years)	Disease: Epilepsy Before or After Meal: Either Single Maximum Dose: 25 mg/kg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: dose may increase 1000 mg/day as needed
Neonates (0 to 1 month)	Disease: Epilepsy Before or After Meal: Either Single Maximum Dose: 20 mg/kg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: dose may increase 1000 mg/day as needed

Primidone Side Effects

Based on research, the following side effects have been observed when Primidone is used -

Common

Drowsiness
Nausea or vomiting
Unsteadiness
Dizziness

Primidone Related Warnings

Is the use of Primidone safe for pregnant women?

Primidone can cause unwanted side effects in pregnant women. If you experience any side effects, stop taking Primidone right away. Take your doctor's advice before taking it again.

Moderate
Is the use of Primidone safe during breastfeeding?

Taking Primidone may lead to serious side effects if you are breastfeeding. Primidone should not be taken by breastfeeding women unless prescribed by the doctor.

Severe
What is the effect of Primidone on the Kidneys?

Primidone rarely affects the kidneys.

Mild
What is the effect of Primidone on the Liver?

Primidone has very mild side effects on the liver.

Mild
What is the effect of Primidone on the Heart?

Primidone is not harmful for the heart.

Safe

Severe Interaction of Primidone with Other Drugs

Primidone should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate

Propranolol

Doxycycline

Quinidine

Chloramphenicol

Paracetamol

Primidone Contraindications

If you are suffering from any of the following diseases, you should not take Primidone unless your doctor advises you to do so -

Osteoporosis
COPD (Chronic Obstructive Pulmonary Disease)
Depression
Suicidal Tendency
Kidney Disease
Liver Disease

Frequently asked Questions about Primidone

Is this Primidone habit forming or addictive?

Yes, you can get addicted to Primidone. It is essential that you take [medicine] only after doctor's recommendation.

Yes
Is it safe to drive or operate heavy machinery when consuming?

No, you should do not do anything that requires concentration and attention as the Primidone can make you feel drowsy.

Dangerous
Is it safe?

Yes, but take Primidone only as per medical advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

Primidone has been seen to have positive effect on patients with mental disorders.

Yes

Primidone Interactions with Food and Alcohol

Interaction between Food and Primidone

Taking Primidone with food does not harm your health.

Safe
Interaction between Alcohol and Primidone

Taking Primidone with alcohol can have severely harmful effects on your health.

Severe

See all substitutes for Primidone

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Mysoline® (primidone)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 413

Primidone Tablet