Dactinomycin Benefits & Uses

Dactinomycin is used to treat the following -

Other Benefits

Dactinomycin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Wilms Tumor Before or After Meal: As advised by a physician Single Maximum Dose: 15 mcg/kg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 5 days Special Instructions: Given as a part of a combination regimen
Geriatric	Disease: Wilms Tumor Before or After Meal: As advised by a physician Single Maximum Dose: 15 mcg/kg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 5 days Special Instructions: Given as a part of a combination regimen
13 - 18 years (Adolescent)	Disease: Wilms Tumor Before or After Meal: As advised by a physician Single Maximum Dose: 15 mcg/kg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 5 days Special Instructions: Given as a part of a combination regimen
2 - 12 years (Child)	Disease: Wilms Tumor Before or After Meal: As advised by a physician Single Maximum Dose: 15 mcg/kg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 5 days Special Instructions: Only given 6 years old and above
Adult(Male)	Disease: Testicular Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 1500 mcg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor
Adult(Female)	Disease: Ovarian Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 500 mcg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 5 days Special Instructions: Repeat every 4 weeks

Dactinomycin Side Effects

Based on research, the following side effects have been observed when Dactinomycin is used -

Common

Nausea or vomiting
Diarrhoea
Hair Loss
Erythema
Rash

Unknown

Mouth ulcer (Read More - How to get rid of Mouth Ulcers)
Loss of appetite
Inflammation Of Rectum
Infection
Injection Site Allergic Reaction
Anemia (Read More - Home Remedies for Anaemia)
Hepatitis

Dactinomycin Related Warnings

Is the use of Dactinomycin safe for pregnant women?

Dactinomycin has many dangerous side effects in pregnant women. If you are pregnant, do not consume Dactinomycin without medical advice.

Severe
Is the use of Dactinomycin safe during breastfeeding?

Women who are breastfeeding, may experience serious side effects after taking Dactinomycin. So it is adviced to consult the doctor before using it.

Severe
What is the effect of Dactinomycin on the Kidneys?

Very few cases of side effects of Dactinomycin on kidney have been reported.

Mild
What is the effect of Dactinomycin on the Liver?

Very few cases of side effects of Dactinomycin on the liver have been reported.

Mild
What is the effect of Dactinomycin on the Heart?

There are no any side effects of Dactinomycin for the heart.

Safe

Severe Interaction of Dactinomycin with Other Drugs

Dactinomycin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Clozapine

Ibuprofen

Moderate

Busulfan

Interferon Alpha 2B

Interferon Beta-1A

Anakinra

Anakinra Injection

Dactinomycin Contraindications

If you are suffering from any of the following diseases, you should not take Dactinomycin unless your doctor advises you to do so -

Liver Disease
Kidney Disease
Calcium Deficiency
Herpes

Frequently asked Questions about Dactinomycin

Is this Dactinomycin habit forming or addictive?

No, you will not get addicted to Dactinomycin.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should do not do anything that requires concentration and attention as the Dactinomycin can make you feel drowsy.

Dangerous
Is it safe?

Yes, but take Dactinomycin only as per medical advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, Dactinomycin cannot treat any kind of mental disorder.

No

Dactinomycin Interactions with Food and Alcohol

Interaction between Food and Dactinomycin

Taking Dactinomycin with food does not harm your health.

Safe
Interaction between Alcohol and Dactinomycin

No research has been done on this till date. Therefore, it is not known what the effect of taking Dactinomycin with alcohol will be.

Unknown

See all substitutes for Dactinomycin

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 867

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Cosmegen® (dactinomycin)

Dactinomycin Injection