Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Vildamac M treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Vildamac M induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Dr. Manju Shekhawat MBBS , General Physician

No, you should not take alcohol with Vildamac M, because it can cause serious side effects which includes hypoglycemia (low blood sugar). The risk of hypoglycemia is higher when you're drinking and taking Vildamac M than if you're just taking Vildamac M. Some of the signs of hypoglycemia include dizziness, confusion, and drowsiness.

Dr. Vedprakash Verma MBBS, MD , Cardiology

Yes, Vildamac M is safe to use, many people have side effects at first, they usually diminish and then go away completely in a few weeks. A few people find they cannot tolerate metformin, there are other drugs but metformin is usually the first choice. It is very safe

Dr. Bharat MBBS , General Physician

The long-term use can lead to the deficiency of Vitamin B12, which can further lead to megaloblastic anemia. Furthermore, Long-term Metformin use can also lead to kidney and liver problems. 

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Vildamac M works by decreasing the hepatic glucose production. It also works to lower blood sugar by increasing your sensitivity to insulin and decreasing the amount of glucose that is absorbed from the food you eat.