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Topgraf, a prescription drug, is manufactured in various forms such as Ointment. It is primarily used for the treatment of Liver transplant, Kidney transplant, Heart Transplant. Other than this, Topgraf has some other therapeutic uses, which have been discussed ahead.
The correct dosage of Topgraf depends on the patient's age, gender, and medical history. The condition it has been prescribed for, and the route of administration also determine the right dosage. Refer to the dosage section for a detailed discussion.
Apart from the aforementioned side effects, Topgraf can also lead to other problems, which have been listed below. These side effects of Topgraf are usually temporary and subside with the completion of treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.
Topgraf's effect during pregnancy is Moderate and Moderate while nursing. It is important to know if Topgraf has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Topgraf related warnings section.
Topgraf is not recommended if you suffer from certain medical conditions as it can have adverse effects. Infections, Diabetes Type 2 are examples of such conditions. Other contraindications of Topgraf have been discussed in the sections ahead.
Additionally, Topgraf may also adversely react with other medicines. See below for a complete list.
In addition to these precautions, you may also note that Topgraf is safe while driving, and is is addictive in nature.
Topgraf is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
|
| Geriatric |
|
| 13 - 18 years (Adolescent) |
|
| 2 - 12 years (Child) |
|
Is the use of Topgraf safe for pregnant women?
Topgraf can cause unwanted side effects in pregnant women. If you experience any side effects, stop taking Topgraf right away. Take your doctor's advice before taking it again.
Is the use of Topgraf safe during breastfeeding?
Topgraf may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Topgraf, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Topgraf.
What is the effect of Topgraf on the Kidneys?
Topgraf may cause harmful effects on kidney. if you feel its having any such effect, then stop taking this drug, and restart only on your doctor's advice.
What is the effect of Topgraf on the Liver?
Topgraf can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.
What is the effect of Topgraf on the Heart?
There may be severe side effects of Topgraf on your heart. Do not take it unless a doctor says so.
Topgraf should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Topgraf unless your doctor advises you to do so -
Is this Topgraf habit forming or addictive?
Forming a habit of Topgraf has not been reported.
Is it safe to drive or operate heavy machinery when consuming?
Topgraf will not make you feel sleepy or drowsy. So you drive or operate machinery safely.
Is it safe?
Topgraf is safe but it is important to consult a doctor before taking it.
Is it able to treat mental disorders?
Topgraf is unable to treat or cure mental disorders.
Interaction between Food and Topgraf
There isn't any research available on the side effects of taking Topgraf with food.
Interaction between Alcohol and Topgraf
Consuming Topgraf with alcohol can have many serious effects on your body.
Topgraf work by reducing the activity of the immune system so it cannot attack the transplanted organ. Hence in this way, it prevents the rejection of organ transplants.
Yes, Topgraf may cause hair loss. The patients who are taking this drug are at risk of alopecia (hair loss). If you are experiencing the same after taking this drug, you are advised to consult about it with your doctor immediately.
Yes, you can discontinue the Topgraf once you get the relief from burns. You are recommended to consult a doctor before discontinuing this medicine.
Yes, Topgraf is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as headache, diarrhea, constipation, nausea, vomiting. If you experience any discomfort after taking this do inform your doctor.
Yes, Topgraf may cause a headache. It has been reported by the patients who are taking this drug. If you are experiencing the same after taking this drug, you are advised to consult about it with your doctor.
This medicine data has been created by -
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Prograf® (tacrolimus)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 881
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1165-1167
